UniProt Q6UX04
Peptidyl-prolyl cis-trans isomerase CWC27 homolog (Q6UX04)
Peptidyl-prolyl cis-trans isomerase CWC27 homolog (UniProt Q6UX04), EC 5.2.1.8: 15 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q6UX04
- Protein
- Peptidyl-prolyl cis-trans isomerase CWC27 homolog
- EC
- 5.2.1.8
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
16 records of Q6UX04 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2HQ6 | Structure of the Cyclophilin_CeCYP16-Like Domain of the Serologically Defined Colon Cancer Antigen… | x-ray diffraction | A | — | — |
| 2HQ6 | Structure of the CYCLOPHILIN_CECYP16-like domain of the serologically defined colon cancer antigen… | x-ray diffraction | A | — | — |
| 4R3E | Structure of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27 from Homo sapiens | x-ray diffraction | A | — | — |
| 4R3E | Structure of the spliceosomal peptidyl-prolyl cis-trans isomerase CWC27 from homo sapiens | x-ray diffraction | A | — | — |
| 5Z56 | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | electron microscopy | z | — | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | electron microscopy | z | — | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. | electron microscopy | z | — | — |
| 6FF4 | human Bact spliceosome core structure | electron microscopy | s | — | — |
| 6FF4 | Human bact spliceosome core structure | electron microscopy | s | — | — |
| 6FF7 | human Bact spliceosome core structure | electron microscopy | s | — | 1 (best 0.81) |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | s | — | — |
| 6YVH | CWC22-CWC27-EIF4A3 complex | x-ray diffraction | C, I, E, G | — | — |
| 7DVQ | Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | electron microscopy | z | — | — |
| 7DVQ | Cryo-EM structure of the activated human minor spliceosome (minor bact complex) | electron microscopy | z | — | — |
| 8I0R | The cryo-EM structure of human Bact-I complex | electron microscopy | z | — | 1 (best 0.82) |
| Q6UX04 | AlphaFold monomer V2.0 prediction for spliceosome-associated protein CWC27 homolog (Q6UX04) | predicted | A | — | — |
Experiment against prediction
- 7DVQ chain z against the predicted model Q6UX04: TM-score 0.99, RMSD 0.60 Å
- 7DVQ chain z against the predicted model Q6UX04: TM-score 0.99, RMSD 0.60 Å
- 4R3E chain A against the predicted model Q6UX04: TM-score 0.99, RMSD 0.67 Å
- 4R3E chain A against the predicted model Q6UX04: TM-score 0.99, RMSD 0.67 Å
- 8I0R chain z against the predicted model Q6UX04: TM-score 0.98, RMSD 0.69 Å
- 5Z56 chain z against the predicted model Q6UX04: TM-score 0.98, RMSD 0.82 Å
- 5Z58 chain z against the predicted model Q6UX04: TM-score 0.98, RMSD 0.82 Å
- 5Z58 chain z against the predicted model Q6UX04: TM-score 0.98, RMSD 0.82 Å
- 2HQ6 chain A against the predicted model Q6UX04: TM-score 0.98, RMSD 0.88 Å
- 2HQ6 chain A against the predicted model Q6UX04: TM-score 0.98, RMSD 0.88 Å
Elsewhere
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