UniProt Q6UUV9
CRTC1 pSer151 peptide (Q6UUV9)
CRTC1 pSer151 peptide (UniProt Q6UUV9): 6 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6UUV9
- Protein
- CRTC1 pSer151 peptide
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 14 · 6 records with a druggable one
Structures
7 records of Q6UUV9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7D8H | CRTC1 pSer64 peptide in complex with 14-3-3 zeta | x-ray diffraction | B | — | 1 (best 0.59) |
| 7D8H | CRTC1 PSER64 peptide in complex with 14-3-3 zeta | x-ray diffraction | B | — | 1 (best 0.59) |
| 7D8P | CRTC1 pSer151 peptide in complex with 14-3-3 zeta | x-ray diffraction | C, D | — | 4 (best 0.66) |
| 7D8P | CRTC1 PSER151 peptide in complex with 14-3-3 zeta | x-ray diffraction | C, D | — | 4 (best 0.66) |
| 7D9V | CRTC1 pSer245 peptide in complex with 14-3-3 zeta | x-ray diffraction | C, D | — | 2 (best 0.71) |
| 7D9V | CRTC1 PSER245 peptide in complex with 14-3-3 zeta | x-ray diffraction | C, D | — | 2 (best 0.71) |
| Q6UUV9 | AlphaFold monomer V2.0 prediction for creb-regulated transcription coactivator 1 (Q6UUV9) | predicted | A | — | — |
Experiment against prediction
- 7D9V chain C against the predicted model Q6UUV9: TM-score 0.52, RMSD 1.02 Å
- 7D9V chain C against the predicted model Q6UUV9: TM-score 0.52, RMSD 1.02 Å
- 7D8H chain B against the predicted model Q6UUV9: TM-score 0.43, RMSD 0.86 Å
- 7D8H chain B against the predicted model Q6UUV9: TM-score 0.43, RMSD 0.86 Å
- 7D9V chain D against the predicted model Q6UUV9: TM-score 0.42, RMSD 0.90 Å
- 7D9V chain D against the predicted model Q6UUV9: TM-score 0.42, RMSD 0.90 Å
- 7D8P chain C against the predicted model Q6UUV9: TM-score 0.39, RMSD 1.13 Å
- 7D8P chain C against the predicted model Q6UUV9: TM-score 0.39, RMSD 1.13 Å
- 7D8P chain D against the predicted model Q6UUV9: TM-score 0.38, RMSD 1.28 Å
- 7D8P chain D against the predicted model Q6UUV9: TM-score 0.38, RMSD 1.28 Å
Elsewhere
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