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UniProt Q6PRR9

Aspartic protease PM5 (Q6PRR9)

Aspartic protease PM5 (UniProt Q6PRR9): 4 experimental structures on GenesisL1, 5 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q6PRR9
Protein
Aspartic protease PM5
Experimental structures
4
Predicted models
0
Ligands
5
Pockets
6 · 2 records with a druggable one

Structures

4 records of Q6PRR9 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4ZL4Plasmepsin V from Plasmodium vivax bound to a transition state mimetic (WEHI-842)x-ray diffractionA, B4PK, SO4, 4PF5 (best 0.74)
4ZL4Plasmepsin V from plasmodium vivax bound to a transition state mimetic (wehi-842)x-ray diffractionA, B——
6C4GPlasmepsin V from Plasmodium vivax bound to a transition state mimetic (WEHI-601)x-ray diffractionANAG, EQG1 (best 0.67)
6C4GPlasmepsin V from plasmodium vivax bound to a transition state mimetic (wehi-601)x-ray diffractionANAG, EQG—

Ligands

  • EQG · benzyl [(6S,7S,10S,13S,18Z)-18-amino-10-cyclohexyl-6-hydroxy-18-imino-7-(2-methylpropyl)-4,9,12-trioxo-1-phenyl-16-oxa-3,8,11,17-tetraazaoctadecan-13-yl]carbamate · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • 4PF · (2R)-1-[(2R)-2-(2-methoxyethoxy)propoxy]propan-2-amine · in 1 record
  • 4PK · N-[(benzyloxy)carbonyl]-O-carbamimidamido-L-homoseryl-N-{(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-[(2-phenylethyl)amino]heptan-4-yl}-L-valinamide · in 1 record
  • SO4 · Sulfate ion · in 1 record

Elsewhere

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