UniProt Q6PI25
Protein cornichon homolog 2 (Q6PI25)
Protein cornichon homolog 2 (UniProt Q6PI25): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PI25
- Protein
- Protein cornichon homolog 2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 5 records with a druggable one
Structures
7 records of Q6PI25 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8SS2 | Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound… | electron microscopy | E, F | PCW | 2 (best 0.59) |
| 8SS3 | Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and… | electron microscopy | E, F | PCW | 2 (best 0.54) |
| 8SS6 | Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound… | electron microscopy | E, F | CLR, PCW | — |
| 8SS7 | Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound… | electron microscopy | E, F | CLR, PCW | 2 (best 0.59) |
| 8SSA | Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound… | electron microscopy | E, F | PCW | 2 (best 0.66) |
| 8SSB | Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and… | electron microscopy | E, F | PCW | 2 (best 0.62) |
| Q6PI25 | AlphaFold monomer V2.0 prediction for protein cornichon homolog 2 (Q6PI25) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8SSB chain F against the predicted model Q6PI25: TM-score 0.92, RMSD 1.60 Å
- 8SSB chain E against the predicted model Q6PI25: TM-score 0.92, RMSD 1.62 Å
- 8SSA chain E against the predicted model Q6PI25: TM-score 0.92, RMSD 1.62 Å
- 8SSA chain F against the predicted model Q6PI25: TM-score 0.92, RMSD 1.61 Å
- 8SS3 chain E against the predicted model Q6PI25: TM-score 0.92, RMSD 1.74 Å
- 8SS3 chain F against the predicted model Q6PI25: TM-score 0.92, RMSD 1.74 Å
- 8SS7 chain F against the predicted model Q6PI25: TM-score 0.92, RMSD 1.75 Å
- 8SS7 chain E against the predicted model Q6PI25: TM-score 0.92, RMSD 1.75 Å
- 8SS6 chain E against the predicted model Q6PI25: TM-score 0.92, RMSD 1.78 Å
- 8SS6 chain F against the predicted model Q6PI25: TM-score 0.92, RMSD 1.78 Å
Elsewhere
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