UniProt Q6PHZ2
Calcium/calmodulin-dependent protein kinase type II subunit delta (Q6PHZ2)
Calcium/calmodulin-dependent protein kinase type II subunit delta (UniProt Q6PHZ2), EC 2.7.11.17: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 21 pockets. Binding sites, druggability and…
- UniProt
- Q6PHZ2
- Protein
- Calcium/calmodulin-dependent protein kinase type II subunit delta
- EC
- 2.7.11.17
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 21 · 2 records with a druggable one
Structures
3 records of Q6PHZ2 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BAB | The structure of human CamKII with bound inhibitor | x-ray diffraction | A, B, C, D | D0S | 15 (best 0.78) |
| 6BAB | The structure of human camkii with bound inhibitor | x-ray diffraction | A, B, C, D | D0S | — |
| Q6PHZ2 | AlphaFold monomer V2.0 prediction for CALCIUM/CALMODULIN-dependent protein kinase type II subunit… | predicted | A | — | 6 (best 0.79) |
Ligands
- D0S · N-[(2S)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide · in 2 records
Experiment against prediction
- 6BAB chain D against the predicted model Q6PHZ2: TM-score 0.98, RMSD 0.92 Å
- 6BAB chain D against the predicted model Q6PHZ2: TM-score 0.98, RMSD 0.92 Å
- 6BAB chain B against the predicted model Q6PHZ2: TM-score 0.98, RMSD 0.93 Å
- 6BAB chain B against the predicted model Q6PHZ2: TM-score 0.98, RMSD 0.93 Å
- 6BAB chain C against the predicted model Q6PHZ2: TM-score 0.96, RMSD 1.43 Å
- 6BAB chain C against the predicted model Q6PHZ2: TM-score 0.96, RMSD 1.43 Å
- 6BAB chain A against the predicted model Q6PHZ2: TM-score 0.96, RMSD 1.47 Å
- 6BAB chain A against the predicted model Q6PHZ2: TM-score 0.96, RMSD 1.47 Å
Elsewhere
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