UniProt Q6PD62
RNA polymerase-associated protein CTR9 homolog (Q6PD62)
RNA polymerase-associated protein CTR9 homolog (UniProt Q6PD62): 14 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PD62
- Protein
- RNA polymerase-associated protein CTR9 homolog
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 10 · 5 records with a druggable one
Structures
15 records of Q6PD62 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZYQ | The structure of human PAF1/CTR9 complex | x-ray diffraction | A | — | — |
| 6GMH | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | electron microscopy | Q | — | — |
| 6GMH | Structure of activated transcription complex pol II-dsif-paf-SPT6 | electron microscopy | Q | — | — |
| 6TED | Structure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric… | electron microscopy | Q | — | — |
| 7OOP | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | electron microscopy | S | — | — |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | S | — | — |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | S | — | — |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | S | — | — |
| 7UNC | Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome | electron microscopy | Q | — | — |
| 7UND | Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | electron microscopy | Q | — | 2 (best 0.83) |
| 8A3Y | Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex | electron microscopy | Q, U | — | 3 (best 0.84) |
| 9EGX | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27 | electron microscopy | Q | — | 2 (best 0.84) |
| 9EGY | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27 | electron microscopy | Q | — | 2 (best 0.83) |
| 9EH2 | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream | electron microscopy | Q | — | 1 (best 0.84) |
| Q6PD62 | AlphaFold monomer V2.0 prediction for RNA polymerase-associated protein CTR9 homolog (Q6PD62) | predicted | A | — | — |
Experiment against prediction
- 7OOP chain S against the predicted model Q6PD62: TM-score 0.91, RMSD 3.25 Å
- 7OOP chain S against the predicted model Q6PD62: TM-score 0.91, RMSD 3.25 Å
- 7OPC chain S against the predicted model Q6PD62: TM-score 0.91, RMSD 3.25 Å
- 7OPD chain S against the predicted model Q6PD62: TM-score 0.91, RMSD 3.25 Å
- 9EH2 chain Q against the predicted model Q6PD62: TM-score 0.91, RMSD 3.42 Å
- 9EGX chain Q against the predicted model Q6PD62: TM-score 0.91, RMSD 3.45 Å
- 9EGY chain Q against the predicted model Q6PD62: TM-score 0.91, RMSD 3.45 Å
- 6TED chain Q against the predicted model Q6PD62: TM-score 0.90, RMSD 3.46 Å
- 8A3Y chain Q against the predicted model Q6PD62: TM-score 0.90, RMSD 3.46 Å
- 7UNC chain Q against the predicted model Q6PD62: TM-score 0.90, RMSD 3.50 Å
Elsewhere
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