UniProt Q6P823
H3 histone (Q6P823)
H3 histone (UniProt Q6P823): 6 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6P823
- Protein
- H3 histone
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 14 · 6 records with a druggable one
Structures
7 records of Q6P823 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2H9M | WDR5 in complex with unmodified H3K4 peptide | x-ray diffraction | B, D | — | 3 (best 0.73) |
| 2H9M | WDR5 in complex with unmodified H3K4 peptide | x-ray diffraction | B, D | — | 3 (best 0.73) |
| 2H9N | WDR5 in complex with monomethylated H3K4 peptide | x-ray diffraction | B, D | — | 3 (best 0.74) |
| 2H9N | WDR5 in complex with monomethylated H3K4 peptide | x-ray diffraction | B, D | — | 3 (best 0.74) |
| 2H9P | WDR5 in complex with trimethylated H3K4 peptide | x-ray diffraction | B | — | 1 (best 0.74) |
| 2H9P | WDR5 in complex with trimethylated H3K4 peptide | x-ray diffraction | B | — | 1 (best 0.74) |
| Q6P823 | AlphaFold monomer V2.0 prediction for histone H3.3 (Q6P823) | predicted | A | — | — |
Experiment against prediction
- 2H9P chain B against the predicted model Q6P823: TM-score 0.98, RMSD 0.07 Å
- 2H9P chain B against the predicted model Q6P823: TM-score 0.98, RMSD 0.07 Å
- 2H9N chain B against the predicted model Q6P823: TM-score 0.81, RMSD 0.27 Å
- 2H9N chain B against the predicted model Q6P823: TM-score 0.81, RMSD 0.27 Å
- 2H9M chain D against the predicted model Q6P823: TM-score 0.70, RMSD 0.57 Å
- 2H9M chain D against the predicted model Q6P823: TM-score 0.70, RMSD 0.57 Å
- 2H9M chain B against the predicted model Q6P823: TM-score 0.48, RMSD 0.64 Å
- 2H9M chain B against the predicted model Q6P823: TM-score 0.48, RMSD 0.64 Å
Elsewhere
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