UniProt Q6NYR1
P2X purinoceptor (Q6NYR1)
P2X purinoceptor (UniProt Q6NYR1): 12 experimental structures on GenesisL1, 8 ligands bound, 43 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q6NYR1
- Protein
- P2X purinoceptor
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 43 · 3 records with a druggable one
Structures
12 records of Q6NYR1 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3H9V | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 Angstroms | x-ray diffraction | A | NAG, GD | 2 (best 0.35) |
| 3H9V | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 ångströms | x-ray diffraction | A | — | — |
| 3I5D | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3) | x-ray diffraction | A, B, C | NAG | 9 (best 0.87) |
| 3I5D | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 ångströms (R3) | x-ray diffraction | A, B, C | — | — |
| 4DW0 | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 2.9 Angstroms | x-ray diffraction | A | NAG, BMA, MAN, GD | 3 (best 0.34) |
| 4DW0 | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 2.9 ångströms | x-ray diffraction | A | — | — |
| 4DW1 | Crystal structure of the ATP-gated P2X4 ion channel in the ATP-bound, open state at 2.8 Angstroms | x-ray diffraction | A | NAG, MAN, ATP | 3 (best 0.43) |
| 4DW1 | Crystal structure of the ATP-gated P2X4 ion channel in the ATP-bound, open state at 2.8 ångströms | x-ray diffraction | A | — | — |
| 5WZY | Crystal structure of the P2X4 receptor from zebrafish in the presence of CTP at 2.8 Angstroms | x-ray diffraction | A | NAG, MAN, CTP | 2 (best 0.39) |
| 5WZY | Crystal structure of the P2X4 receptor from zebrafish in the presence of CTP at 2.8 ångströms | x-ray diffraction | A | NAG, MAN, CTP | — |
| 8JV5 | Cryo-EM structure of the zebrafish P2X4 receptor in complex with BX430 | electron microscopy | A, B, C | P73, NAG | 11 (best 0.87) |
| 8JV6 | Cryo-EM structure of the zebrafish P2X4 receptor in complex with BAY-1797 | electron microscopy | A, B, C | NAG, P6E | 13 (best 0.85) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
- MAN · alpha-D-mannopyranose · in 4 records
- CTP · Cytidine-5'-triphosphate · in 2 records
- GD · Gadolinium atom · in 2 records
- ATP · Adenosine-5'-triphosphate · in 1 record
- BMA · beta-D-mannopyranose · in 1 record
- P6E · N-[4-(3-chloranylphenoxy)-3-sulfamoyl-phenyl]-2-phenyl-ethanamide · in 1 record
- P73 · 1-[2,6-bis(bromanyl)-4-propan-2-yl-phenyl]-3-pyridin-3-yl-urea · in 1 record
Elsewhere
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