UniProt Q6IYF9
Succinate receptor 1 (Q6IYF9)
Succinate receptor 1 (UniProt Q6IYF9): 6 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6IYF9
- Protein
- Succinate receptor 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 18 · 4 records with a druggable one
Structures
7 records of Q6IYF9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6IBB | Crystal structure of the rat isoform of the succinate receptor SUCNR1 (GPR91) in complex with a… | x-ray diffraction | A, C | H95, CLR | 9 (best 0.71) |
| 6IBB | Crystal structure of the rat isoform of the succinate receptor SUCNR1 (GPR91) in complex with a… | x-ray diffraction | A, C | H95, CLR | — |
| 6RNK | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex… | x-ray diffraction | A | KAZ, SO4 | 4 (best 0.72) |
| 6RNK | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex… | x-ray diffraction | A | KAZ, SO4 | — |
| 6Z10 | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex… | x-ray diffraction | A | Q4T, SO4, CL | 3 (best 0.72) |
| 6Z10 | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex… | x-ray diffraction | A | Q4T, SO4, CL | — |
| Q6IYF9 | AlphaFold monomer V2.0 prediction for succinate receptor 1 (Q6IYF9) | predicted | A | — | 2 (best 0.57) |
Ligands
- SO4 · Sulfate ion · in 4 records
- CL · Chloride ion · in 2 records
- CLR · Cholesterol · in 2 records
- H95 · (2~{S},5~{R})-hexane-2,5-diol · in 2 records
- KAZ · 2-[2-[[3-[4-[(4-methylpiperazin-1-yl) methyl]phenyl]phenyl]carbonylamino]phenyl]ethanoic acid · in 2 records
- Q4T · 2-[2-[[3-[4-chloranyl-2-fluoranyl-5-[(3~{R})-piperidin-3-yl]oxy-phenyl]-2-fluoranyl-phenyl]carbonylamino]-5-fluoranyl-phenyl]ethanoic acid · in 2 records
Experiment against prediction
- 6RNK chain A against the predicted model Q6IYF9: TM-score 0.99, RMSD 0.47 Å
- 6RNK chain A against the predicted model Q6IYF9: TM-score 0.99, RMSD 0.47 Å
- 6Z10 chain A against the predicted model Q6IYF9: TM-score 0.99, RMSD 0.51 Å
- 6Z10 chain A against the predicted model Q6IYF9: TM-score 0.99, RMSD 0.51 Å
- 6IBB chain C against the predicted model Q6IYF9: TM-score 0.98, RMSD 0.99 Å
- 6IBB chain C against the predicted model Q6IYF9: TM-score 0.98, RMSD 0.99 Å
- 6IBB chain A against the predicted model Q6IYF9: TM-score 0.95, RMSD 1.07 Å
- 6IBB chain A against the predicted model Q6IYF9: TM-score 0.95, RMSD 1.07 Å
Elsewhere
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