UniProt Q6FLB1
Transcription elongation factor SPT6 (Q6FLB1)
Transcription elongation factor SPT6 (UniProt Q6FLB1): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 55 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6FLB1
- Protein
- Transcription elongation factor SPT6
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 55 · 7 records with a druggable one
Structures
9 records of Q6FLB1 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3GXW | Structure of the SH2 domain of the Candida glabrata transcription elongation factor Spt6, crystal… | x-ray diffraction | A, B, C, D | NA | 9 (best 0.57) |
| 3GXW | Structure of the SH2 domain of the candida glabrata transcription elongation factor SPT6, crystal… | x-ray diffraction | A, B, C, D | NA | 9 (best 0.57) |
| 3GXX | Structure of the SH2 domain of the Candida glabrata transcription elongation factor Spt6, crystal… | x-ray diffraction | A, B, C, D | — | 5 (best 0.76) |
| 3GXX | Structure of the SH2 domain of the candida glabrata transcription elongation factor SPT6, crystal… | x-ray diffraction | A, B, C, D | — | 5 (best 0.76) |
| 3PJP | A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase… | x-ray diffraction | A, B | — | 3 (best 0.60) |
| 3PJP | A tandem SH2 domain in transcription elongation factor SPT6 binds the phosphorylated RNA polymerase… | x-ray diffraction | A, B | — | 3 (best 0.60) |
| 6QTC | tSH2 domain of transcription elongation factor Spt6 complexed with tyrosine phosphorylated CTD | solution nmr | A | — | 1 (best 0.39) |
| 6QTC | TSH2 domain of transcription elongation factor SPT6 complexed with tyrosine phosphorylated ctd | solution nmr | A | — | 1 (best 0.39) |
| Q6FLB1 | AlphaFold monomer V2.0 prediction for transcription elongation factor SPT6 (Q6FLB1) | predicted | A | — | 19 (best 0.74) |
Ligands
- NA · Sodium ion · in 2 records
Experiment against prediction
- 3PJP chain B against the predicted model Q6FLB1: TM-score 0.94, RMSD 1.56 Å
- 3PJP chain B against the predicted model Q6FLB1: TM-score 0.94, RMSD 1.56 Å
- 3PJP chain A against the predicted model Q6FLB1: TM-score 0.93, RMSD 1.67 Å
- 3PJP chain A against the predicted model Q6FLB1: TM-score 0.93, RMSD 1.67 Å
- 3GXX chain D against the predicted model Q6FLB1: TM-score 0.83, RMSD 1.89 Å
- 3GXX chain D against the predicted model Q6FLB1: TM-score 0.83, RMSD 1.89 Å
- 3GXW chain D against the predicted model Q6FLB1: TM-score 0.83, RMSD 1.88 Å
- 3GXW chain D against the predicted model Q6FLB1: TM-score 0.83, RMSD 1.88 Å
- 3GXW chain B against the predicted model Q6FLB1: TM-score 0.82, RMSD 1.86 Å
- 3GXW chain B against the predicted model Q6FLB1: TM-score 0.82, RMSD 1.86 Å
Elsewhere
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