UniProt Q6F3I7
Dipeptidyl aminopeptidase 4 (Q6F3I7)
Dipeptidyl aminopeptidase 4 (UniProt Q6F3I7), EC 3.4.14.5: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6F3I7
- Protein
- Dipeptidyl aminopeptidase 4
- EC
- 3.4.14.5
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 60 · 3 records with a druggable one
Structures
9 records of Q6F3I7 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YP1 | Crystal structure of dipeptidyl peptidase IV (DPP IV) from Pseudoxanthomonas mexicana WO24 | x-ray diffraction | A, B, C, D | — | 20 (best 0.86) |
| 5YP1 | Crystal structure of dipeptidyl peptidase IV (dpp IV) from pseudoxanthomonas mexicana WO24 | x-ray diffraction | A, B, C, D | — | — |
| 5YP2 | Crystal structure of dipeptidyl peptidase IV (DPP IV) with DPP4 inhibitor from Pseudoxanthomonas… | x-ray diffraction | A, B | 8YC | — |
| 5YP2 | Crystal structure of dipeptidyl peptidase IV (dpp IV) with DPP4 inhibitor from pseudoxanthomonas… | x-ray diffraction | A, B | 8YC | — |
| 5YP3 | Crystal structure of dipeptidyl peptidase IV (DPP IV) with Ile-Pro from Pseudoxanthomonas mexicana | x-ray diffraction | A, B, C, D | — | 20 (best 0.78) |
| 5YP3 | Crystal structure of dipeptidyl peptidase IV (dpp IV) with ile-pro from pseudoxanthomonas mexicana | x-ray diffraction | A, B, C, D | — | — |
| 5YP4 | Crystal structure of dipeptidyl peptidase IV (DPP IV) with Lys-Pro from Pseudoxanthomonas mexicana… | x-ray diffraction | A, B, C, D | — | 20 (best 0.79) |
| 5YP4 | Crystal structure of dipeptidyl peptidase IV (dpp IV) with lys-pro from pseudoxanthomonas mexicana… | x-ray diffraction | A, B, C, D | — | — |
| Q6F3I7 | AlphaFold monomer V2.0 prediction for dipeptidyl aminopeptidase 4 (Q6F3I7) | predicted | A | — | — |
Ligands
- 8YC · (2S,5R)-1-[2-[[1-(hydroxymethyl) cyclopentyl]amino]ethanoyl]pyrrolidine-2,5-dicarbonitrile · in 2 records
Experiment against prediction
- 5YP2 chain A against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.29 Å
- 5YP2 chain A against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.29 Å
- 5YP2 chain B against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.30 Å
- 5YP2 chain B against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.30 Å
- 5YP1 chain B against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.44 Å
- 5YP1 chain B against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.44 Å
- 5YP4 chain A against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.20 Å
- 5YP4 chain A against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.20 Å
- 5YP4 chain D against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.25 Å
- 5YP4 chain D against the predicted model Q6F3I7: TM-score 1.00, RMSD 0.25 Å
Elsewhere
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