UniProt Q68T42
Protease 3C (Q68T42)
Protease 3C (UniProt Q68T42), EC 3.4.22.28: 103 experimental structures on GenesisL1, 93 ligands bound, 134 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q68T42
- Protein
- Protease 3C
- EC
- 3.4.22.28
- Experimental structures
- 103
- Predicted models
- 0
- Ligands
- 93
- Pockets
- 134 · 45 records with a druggable one
Structures
103 records of Q68T42 in the MolNFT archive: 103 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4WM7 | Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril | x-ray diffraction | B, C | — | — |
| 4WM7 | Crystal structure of human enterovirus D68 in complex with pleconaril | x-ray diffraction | B, C | — | — |
| 4WM8 | Crystal Structure of Human Enterovirus D68 | x-ray diffraction | B, C | — | — |
| 4WM8 | Crystal structure of human enterovirus D68 | x-ray diffraction | B, C | — | — |
| 5BNN | Crystal structure of human enterovirus D68 in complex with 6'SL | x-ray diffraction | A, B, C, D | GAL, SIA | 10 (best 0.73) |
| 5BNN | Crystal structure of human enterovirus D68 in complex with 6'SL | x-ray diffraction | A, B, C, D | — | — |
| 5BNO | Crystal structure of human enterovirus D68 in complex with 6'SLN | x-ray diffraction | A, B, C, D | NAG, GAL, SIA | 11 (best 0.74) |
| 5BNO | Crystal structure of human enterovirus D68 in complex with 6'SLN | x-ray diffraction | A, B, C, D | — | — |
| 5BNP | Crystal structure of human enterovirus D68 in complex with 3'SLN | x-ray diffraction | A, B, C, D | — | — |
| 5BNP | Crystal structure of human enterovirus D68 in complex with 3'SLN | x-ray diffraction | A, B, C, D | — | — |
| 6HLN | Crystal structure of human ACBD3 gold domain in complex with 3A protein of enterovirus-D68 | x-ray diffraction | B | — | — |
| 7GNV | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | 60P | 1 (best 0.48) |
| 7GNW | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | H5A | — |
| 7GNX | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | ST0 | 2 (best 0.45) |
| 7GNY | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | YX6 | 1 (best 0.50) |
| 7GNZ | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SZY | 1 (best 0.54) |
| 7GO0 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | YXB | 2 (best 0.57) |
| 7GO1 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | UR7 | 2 (best 0.52) |
| 7GO2 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SVI | 1 (best 0.29) |
| 7GO3 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SVU | 1 (best 0.52) |
| 7GO4 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | K7L | 1 (best 0.57) |
| 7GO5 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TZ9 | 1 (best 0.60) |
| 7GO6 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TJX | 1 (best 0.58) |
| 7GO7 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | HWH | 1 (best 0.51) |
| 7GO9 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | UXD | 1 (best 0.52) |
| 7GOA | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | Z2F | — |
| 7GOC | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SW9 | 2 (best 0.52) |
| 7GOE | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | UXG | 1 (best 0.51) |
| 7GOF | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SX9 | 1 (best 0.47) |
| 7GOG | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TM0 | 1 (best 0.51) |
| 7GOH | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TNU | 2 (best 0.52) |
| 7GOI | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | 89W | 1 (best 0.48) |
| 7GOJ | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TQC | 1 (best 0.59) |
| 7GOK | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | JAW | 1 (best 0.56) |
| 7GOL | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | U9R | 2 (best 0.48) |
| 7GOM | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | T9K | 2 (best 0.53) |
| 7GON | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TT3 | 2 (best 0.50) |
| 7GOO | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TU6 | 1 (best 0.52) |
| 7GOP | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | LRF | 1 (best 0.57) |
| 7GOQ | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TV9 | 2 (best 0.49) |
| 7GOR | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TVR | 2 (best 0.54) |
| 7GOS | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | JFS | 1 (best 0.57) |
| 7GOU | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | UVA | 1 (best 0.55) |
| 7GOV | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SY3 | 1 (best 0.47) |
| 7GOW | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SYX | 1 (best 0.49) |
| 7GOX | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | GVV | 1 (best 0.48) |
| 7GOY | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | K0Y | 1 (best 0.47) |
| 7GOZ | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | SZX | 1 (best 0.29) |
| 7GP1 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | UJK | 1 (best 0.52) |
| 7GP2 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | LPU | 1 (best 0.29) |
| 7GP4 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | U1X | 2 (best 0.51) |
| 7GP6 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | UVJ | 1 (best 0.34) |
| 7GP7 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TE0 | 1 (best 0.47) |
| 7GP8 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | VVG | 1 (best 0.47) |
| 7GP9 | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | STV | 1 (best 0.49) |
| 7GPA | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | U2R | 2 (best 0.41) |
| 7GPC | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | RX7 | 2 (best 0.49) |
| 7GPD | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | AYV | 1 (best 0.51) |
| 7GPE | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TJL | 2 (best 0.53) |
| 7GPG | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex… | x-ray diffraction | A, B | TWC | 1 (best 0.44) |
43 records more on the page itself.
Ligands
- GAL · beta-D-galactopyranose · in 2 records
- SIA · N-acetyl-alpha-neuraminic acid · in 2 records
- W3M · 1H-imidazole-5-carbonitrile · in 2 records
- 0XM · 1,1-diphenylmethanamine · in 1 record
- 4MB · 4-[(methylsulfonyl)amino]benzoic acid · in 1 record
- 60P · 3-methylthiophene-2-carboxylic acid · in 1 record
- 7ZX · 4-bromanyl-1,2-oxazole · in 1 record
- 89W · N-[(3R)-piperidin-3-yl]benzamide · in 1 record
- AYV · 1-[2-methyl-1,3-bis(oxidanyl)propan-2-yl]-3-phenyl-urea · in 1 record
- GOJ · ethyl 1~{H}-pyrazole-4-carboxylate · in 1 record
- GVV · ~{N}-(4-methyl-2-oxidanyl-phenyl)propanamide · in 1 record
- H3R · 5-methyl-3-phenyl-1H-pyrazole · in 1 record
- H5A · 3,4,5-trimethoxybenzoic acid · in 1 record
- HHQ · 4-iodanyl-3~{H}-pyridin-2-one · in 1 record
- HWH · ~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide · in 1 record
- ISK · 2-acetamido-N-(3-bromanylprop-2-ynyl)ethanamide · in 1 record
- IT4 · 4-bromanyl-2-oxidanyl-benzoic acid · in 1 record
- JAW · 1~{H}-indole-5-carboxamide · in 1 record
- JFS · [4-(1H-benzimidazol-1-yl)phenyl]methanol · in 1 record
- K0Y · methyl N-(5-methyl-1,2-oxazole-3-carbonyl)glycinate · in 1 record
- K7L · (4S)-imidazo[1,2-a]pyrimidine-5,7-diol · in 1 record
- LPU · 1-(methanesulfonyl)piperidin-4-ol · in 1 record
- LRF · N~2~-(4-cyano-3-methyl-1,2-thiazol-5-yl)-N~2~-methylglycinamide · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- RX7 · 2-methyl-2-{[(3-methylthiophen-2-yl) methyl]amino}propan-1-ol · in 1 record
- ST0 · N-cyclopentyloxane-4-sulfonamide · in 1 record
- STV · ~{N}-(1,3-benzodioxol-5-ylmethyl)ethanesulfonamide · in 1 record
- SVI · (4S)-[1,2,4]triazolo[4,3-a]pyrazine · in 1 record
- SVU · 1-(1-ethyl-1H-pyrazol-3-yl)-N-methylmethanamine · in 1 record
- SW9 · 4-{[(1M)-buta-1,2-dien-1-yl](methyl)amino}-1lambda~6~-thiane-1,1-dione · in 1 record
Elsewhere
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