UniProt Q65900
Protease 2A (Q65900)
Protease 2A (UniProt Q65900), EC 3.4.22.29: 24 experimental structures on GenesisL1, 25 ligands bound, 25 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q65900
- Protein
- Protease 2A
- EC
- 3.4.22.29
- Experimental structures
- 24
- Predicted models
- 0
- Ligands
- 25
- Pockets
- 25 · 6 records with a druggable one
Structures
24 records of Q65900 in the MolNFT archive: 24 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7H2W | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | A1AMZ, ZN, SO4 | — |
| 7H2X | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, A1AM0 | 3 (best 0.48) |
| 7H30 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, NWY | — |
| 7H32 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | 89W, ZN | — |
| 7H35 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | TQC, ZN, SO4 | — |
| 7H3A | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | STV, ZN | 1 (best 0.48) |
| 7H3L | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | ZUG, ZN, SO4 | — |
| 7H3N | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | K24, ZN | — |
| 7H3S | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | YG5, ZN, SO4 | — |
| 7H3W | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, NZ1 | 3 (best 0.49) |
| 7H45 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | A1ANA, ZN, SO4 | — |
| 7H46 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | O2A, ZN, SO4 | 1 (best 0.48) |
| 7H4B | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | K2S, ZN, SO4 | — |
| 7H4C | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | VW4, ZN | 1 (best 0.50) |
| 7H4E | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | S07, ZN, SO4 | 1 (best 0.58) |
| 7H4J | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | TE0, ZN | 1 (best 0.51) |
| 7H4L | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | TJL, ZN, SO4 | 1 (best 0.40) |
| 7H4P | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | LGA, ZN, SO4 | — |
| 7H50 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, A1ANH | 3 (best 0.52) |
| 7H52 | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, ZCI | — |
| 7HOE | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, WKY | 3 (best 0.51) |
| 7HOF | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, NZ1 | 3 (best 0.49) |
| 7HOG | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A | YYI, ZN, SO4 | — |
| 7HOH | Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease… | x-ray diffraction | A, B | ZN, A1BF7 | 4 (best 0.52) |
Ligands
- ZN · Zinc ion · in 24 records
- SO4 · Sulfate ion · in 11 records
- NZ1 · 5-methoxy-1,3-benzothiazol-2-amine · in 2 records
- 89W · N-[(3R)-piperidin-3-yl]benzamide · in 1 record
- A1AM0 · 3-methyl-N-{[(3R)-oxolan-3-yl]methyl}-1,2-oxazole-5-carboxamide · in 1 record
- A1AMZ · (4R)-imidazo[1,2-b]pyridazine-3-sulfonamide · in 1 record
- A1ANA · 4-amino-N-cyclobutyl-1-methyl-1H-pyrazole-3-carboxamide · in 1 record
- A1ANH · 1,3-oxazole-4-carbonitrile · in 1 record
- A1BF7 · (3S)-1-(methoxyacetyl)piperidine-3-carboxamide · in 1 record
- K24 · N,2-dimethyl-1,3-thiazole-5-carboxamide · in 1 record
- K2S · N,N,3,5-tetramethyl-1H-pyrazole-4-sulfonamide · in 1 record
- LGA · Pyrimidin-2-amine · in 1 record
- NWY · N-[(6-methylpyridin-3-yl)methyl]cyclobutanecarboxamide · in 1 record
- O2A · N-methyl-1H-indole-7-carboxamide · in 1 record
- S07 · 2-(2,4-dimethylphenoxy)-1-morpholin-4-yl-ethanone · in 1 record
- STV · ~{N}-(1,3-benzodioxol-5-ylmethyl)ethanesulfonamide · in 1 record
- TE0 · 1-(ethanesulfonyl)piperidine-4-carboxylic acid · in 1 record
- TJL · 4-(1,2,4-oxadiazol-5-yl)aniline · in 1 record
- TQC · (3M)-5-cyclobutyl-3-(1-methyl-1H-imidazol-2-yl)-1,2,4-oxadiazole · in 1 record
- VW4 · (2S)-2-phenylpropane-1-sulfonamide · in 1 record
- WKY · N-(3-methylpyridin-4-yl)acetamide · in 1 record
- YG5 · 2-(1H-indazol-1-yl)-N,N-dimethylacetamide · in 1 record
- YYI · 5-(difluoromethoxy)pyridin-2(3H)-one · in 1 record
- ZCI · 2-bromo-1H-imidazole · in 1 record
- ZUG · N,N-dimethylpyridine-3-sulfonamide · in 1 record
Elsewhere
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