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Ligand · UVS

UVS · 5-(methoxymethyl)-1,3,4-thiadiazol-2-amine

UVS, 5-(methoxymethyl)-1,3,4-thiadiazol-2-amine (C4 H7 N3 O S, 145.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
UVS
Formula
C4 H7 N3 O S
Class
ligand
Structures
4
PDB entries
3

Binding sites

UVS in 4 structures; the first of them:

  • 5RK5 · PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z57478994 · UVS A1501 · binds PRO1340, PHE1341, VAL1345, TYR1350, TYR1353, SER1392, TYR1395, THR1396 and 3 more
  • 7H3I · Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A… · UVS A201 · binds LEU31, VAL32
  • 7HMN · PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z57478994 · UVS B202 · binds ASP48, ASN49, LYS50, LYS94
  • 5RK5 · Pandda analysis group deposition -- crystal structure of phip in complex with Z57478994 · UVS A1501 · binds PRO1340, PHE1341, VAL1345, TYR1350, SER1392, TYR1395, THR1396, SER1401 and 1 more

Residues it binds most

TYR 2, SER 2, VAL 3, ILE 2, LYS 1, PHE 2, PRO 2, THR 2, ASN 1, ASP 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid

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