UniProt Q60019
NADH-quinone oxidoreductase subunit 8 (Q60019)
NADH-quinone oxidoreductase subunit 8 (UniProt Q60019), EC 1.6.5.11, 7.1.1.-: 19 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q60019
- Protein
- NADH-quinone oxidoreductase subunit 8
- EC
- 1.6.5.11, 7.1.1.-
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 4 records with a druggable one
Structures
20 records of Q60019 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HE8 | Crystal structure of the membrane domain of respiratory complex I from Thermus thermophilus | x-ray diffraction | H, C | — | — |
| 4HE8 | Crystal structure of the membrane domain of respiratory complex I from thermus thermophilus | x-ray diffraction | H, C | — | — |
| 4HEA | Crystal structure of the entire respiratory complex I from Thermus thermophilus | x-ray diffraction | H, Q | — | — |
| 4HEA | Crystal structure of the entire respiratory complex I from thermus thermophilus | x-ray diffraction | H, Q | — | — |
| 6I0D | Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiqui | x-ray diffraction | H, Q | — | — |
| 6I0D | Respiratory complex I from thermus thermophilus with bound decyl- ubiquinone | x-ray diffraction | H, Q | — | — |
| 6I1P | Respiratory complex I from Thermus thermophilus with bound NADH | x-ray diffraction | H, Q | — | — |
| 6I1P | Respiratory complex I from thermus thermophilus with bound NADH | x-ray diffraction | H, Q | — | — |
| 6Q8O | Respiratory complex I from thermus thermophilus with bound piericidin a | x-ray diffraction | H, Q | HQH | — |
| 6Q8W | Respiratory complex I from thermus thermophilus with bound aureothin. | x-ray diffraction | H, Q | HQW | — |
| 6Q8X | Respiratory complex I from Thermus thermophilus with bound Pyridaben. | x-ray diffraction | H, Q | HQK | 7 (best 0.87) |
| 6Q8X | Respiratory complex I from thermus thermophilus with bound pyridaben. | x-ray diffraction | H, Q | HQK | — |
| 6Y11 | Respiratory complex I from thermus thermophilus | x-ray diffraction | H, Q | — | — |
| 6ZIY | Respiratory complex I from thermus thermophilus, NADH dataset, major state | electron microscopy | H | — | — |
| 6ZJL | Respiratory complex I from Thermus thermophilus, NAD+ dataset, major state | electron microscopy | H | — | 5 (best 0.87) |
| 6ZJL | Respiratory complex I from thermus thermophilus, NAD+ dataset, major state | electron microscopy | H | — | — |
| 6ZJN | Respiratory complex I from thermus thermophilus, NADH dataset, minor state | electron microscopy | H | — | — |
| 6ZJY | Respiratory complex I from Thermus thermophilus, NAD+ dataset, minor state | electron microscopy | H | — | 2 (best 0.83) |
| 6ZJY | Respiratory complex I from thermus thermophilus, NAD+ dataset, minor state | electron microscopy | H | — | — |
| Q60019 | AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit 8 (Q60019) | predicted | A | — | 6 (best 0.72) |
Ligands
Experiment against prediction
- 4HEA chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.23 Å
- 4HEA chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.23 Å
- 6I1P chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.15 Å
- 6I1P chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.15 Å
- 6Q8X chain Q against the predicted model Q60019: TM-score 0.97, RMSD 1.24 Å
- 6ZJL chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.18 Å
- 6ZJL chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.18 Å
- 6Y11 chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.26 Å
- 6Q8W chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.26 Å
- 6ZIY chain H against the predicted model Q60019: TM-score 0.97, RMSD 1.21 Å
Elsewhere
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