UniProt Q5ZXB6
Isocitrate dehydrogenase (Q5ZXB6)
Isocitrate dehydrogenase (UniProt Q5ZXB6), EC 1.1.1.42: 2 experimental structures on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q5ZXB6
- Protein
- Isocitrate dehydrogenase
- EC
- 1.1.1.42
- Experimental structures
- 2
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 4 · 1 record with a druggable one
Structures
2 records of Q5ZXB6 in the MolNFT archive: 2 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6C0E | Crystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an… | x-ray diffraction | A, B | EE1, GLY, CL | 4 (best 0.79) |
| 6C0E | Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound NADPH with an… | x-ray diffraction | A, B | EE1, CL | — |
Ligands
- CL · Chloride ion · in 2 records
- EE1 · (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R}, 4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid · in 2 records
- GLY · Glycine · in 1 record
Elsewhere
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