UniProt Q5Y4Y6
Gasdermin-A3 (Q5Y4Y6)
Gasdermin-A3 (UniProt Q5Y4Y6): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5Y4Y6
- Protein
- Gasdermin-A3
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of Q5Y4Y6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5B5R | Crystal structure of GSDMA3 | x-ray diffraction | A | — | — |
| 5B5R | Crystal structure of GSDMA3 | x-ray diffraction | A | — | — |
| 6CB8 | Cryo-EM structure of the Gasdermin A3 membrane pore | electron microscopy | A | CDL | 1 (best 0.48) |
| 6CB8 | Cryo-EM structure of the gasdermin A3 membrane pore | electron microscopy | A | CDL | — |
| Q5Y4Y6 | AlphaFold monomer V2.0 prediction for gasdermin-A3 (Q5Y4Y6) | predicted | A | — | — |
Ligands
- CDL · Cardiolipin · in 2 records
Experiment against prediction
- 5B5R chain A against the predicted model Q5Y4Y6: TM-score 0.90, RMSD 2.50 Å
- 5B5R chain A against the predicted model Q5Y4Y6: TM-score 0.90, RMSD 2.50 Å
- 6CB8 chain A against the predicted model Q5Y4Y6: TM-score 0.80, RMSD 1.91 Å
- 6CB8 chain A against the predicted model Q5Y4Y6: TM-score 0.80, RMSD 1.91 Å
Elsewhere
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