UniProt Q5VVY1
Alpha N-terminal protein methyltransferase 1B (Q5VVY1)
Alpha N-terminal protein methyltransferase 1B (UniProt Q5VVY1), EC 2.1.1.299: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q5VVY1
- Protein
- Alpha N-terminal protein methyltransferase 1B
- EC
- 2.1.1.299
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 2 records with a druggable one
Structures
9 records of Q5VVY1 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UBB | Crystal structure of human alpha N-terminal protein methyltransferase 1B | x-ray diffraction | A | UNX | — |
| 5UBB | Crystal structure of human alpha N-terminal protein methyltransferase 1B | x-ray diffraction | A | UNX | — |
| 6DUB | Crystal structure of a methyltransferase | x-ray diffraction | A, B | UNX | — |
| 6DUB | Crystal structure of a methyltransferase | x-ray diffraction | A, B | UNX | — |
| 6KDR | Crystal structure of human NRMT2 in complex with human centromere protein B peptide | x-ray diffraction | A, B | CL | — |
| 6KDR | Crystal structure of human NRMT2 in complex with human centromere protein B peptide | x-ray diffraction | A, B | CL | — |
| 6KDS | Crystal structure of human NRMT2 in complex with alpha-N-monomethylated human CENP-A peptide | x-ray diffraction | A | SAH | 1 (best 0.77) |
| 6KDS | Crystal structure of human NRMT2 in complex with alpha-N- monomethylated human cenp-a peptide | x-ray diffraction | A | — | — |
| Q5VVY1 | AlphaFold monomer V2.0 prediction for alpha N-terminal protein methyltransferase 1B (Q5VVY1) | predicted | A | — | 2 (best 0.76) |
Ligands
Experiment against prediction
- 6KDS chain A against the predicted model Q5VVY1: TM-score 0.97, RMSD 1.12 Å
- 6DUB chain B against the predicted model Q5VVY1: TM-score 0.97, RMSD 1.22 Å
- 6DUB chain B against the predicted model Q5VVY1: TM-score 0.97, RMSD 1.22 Å
- 6KDR chain A against the predicted model Q5VVY1: TM-score 0.97, RMSD 1.09 Å
- 6KDR chain A against the predicted model Q5VVY1: TM-score 0.97, RMSD 1.09 Å
- 6KDS chain A against the predicted model Q5VVY1: TM-score 0.97, RMSD 1.12 Å
- 5UBB chain A against the predicted model Q5VVY1: TM-score 0.96, RMSD 1.36 Å
- 5UBB chain A against the predicted model Q5VVY1: TM-score 0.96, RMSD 1.36 Å
- 6DUB chain A against the predicted model Q5VVY1: TM-score 0.96, RMSD 1.28 Å
- 6DUB chain A against the predicted model Q5VVY1: TM-score 0.96, RMSD 1.28 Å
Elsewhere
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