UniProt Q5U5Q3
RNA-binding E3 ubiquitin-protein ligase MEX3C (Q5U5Q3)
RNA-binding E3 ubiquitin-protein ligase MEX3C (UniProt Q5U5Q3), EC 2.3.2.27: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q5U5Q3
- Protein
- RNA-binding E3 ubiquitin-protein ligase MEX3C
- EC
- 2.3.2.27
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 4 · 1 record with a druggable one
Structures
9 records of Q5U5Q3 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WWW | Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex… | x-ray diffraction | A | — | 1 (best 0.27) |
| 5WWW | Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin- protein ligase mex-3C… | x-ray diffraction | A | — | — |
| 5WWX | Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex… | x-ray diffraction | A | NI | — |
| 5WWX | Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin- protein ligase mex-3C… | x-ray diffraction | A | NI | — |
| 5WWZ | Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C | x-ray diffraction | B, A, C | SO4 | 3 (best 0.62) |
| 5WWZ | Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin- protein ligase mex-3C | x-ray diffraction | B, A, C | SO4 | — |
| 5ZI6 | The RING domain structure of MEX-3C | x-ray diffraction | A, B, C, D, E, F, G, H | ZN | — |
| 5ZI6 | The ring domain structure of mex-3C | x-ray diffraction | A, B, C, D, E, F, G, H | ZN | — |
| Q5U5Q3 | AlphaFold monomer V2.0 prediction for RNA-binding E3 ubiquitin- protein ligase MEX3C (Q5U5Q3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5ZI6 chain A against the predicted model Q5U5Q3: TM-score 0.94, RMSD 0.85 Å
- 5ZI6 chain A against the predicted model Q5U5Q3: TM-score 0.94, RMSD 0.85 Å
- 5WWZ chain A against the predicted model Q5U5Q3: TM-score 0.89, RMSD 1.44 Å
- 5WWZ chain A against the predicted model Q5U5Q3: TM-score 0.89, RMSD 1.44 Å
- 5WWZ chain C against the predicted model Q5U5Q3: TM-score 0.88, RMSD 1.52 Å
- 5WWZ chain C against the predicted model Q5U5Q3: TM-score 0.88, RMSD 1.52 Å
- 5WWX chain A against the predicted model Q5U5Q3: TM-score 0.88, RMSD 1.75 Å
- 5WWX chain A against the predicted model Q5U5Q3: TM-score 0.88, RMSD 1.75 Å
- 5WWZ chain B against the predicted model Q5U5Q3: TM-score 0.86, RMSD 1.65 Å
- 5WWZ chain B against the predicted model Q5U5Q3: TM-score 0.86, RMSD 1.65 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.