UniProt Q5TA45
Integrator complex subunit 11 (Q5TA45)
Integrator complex subunit 11 (UniProt Q5TA45), EC 3.1.27.-: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q5TA45
- Protein
- Integrator complex subunit 11
- EC
- 3.1.27.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 1 record with a druggable one
Structures
7 records of Q5TA45 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5V8W | Crystal structure of human integrator INTS9-INTS11 ctd complex | x-ray diffraction | B, D, F, H | — | — |
| 7BFP | Structure of the integrator cleavage module with INTS4/9/11 | electron microscopy | B | — | — |
| 7BFQ | Structure of the Integrator cleavage module with extended INTS4 and rigid body docked INTS9/11 CTD | electron microscopy | B | — | 12 (best 0.87) |
| 7BFQ | Structure of the integrator cleavage module with extended INTS4 and rigid body docked INTS9/11 ctd | electron microscopy | B | — | — |
| 7CUN | The structure of human Integrator-PP2A complex | electron microscopy | K | ZN | — |
| 7CUN | The structure of human integrator-PP2A complex | electron microscopy | K | ZN | — |
| Q5TA45 | AlphaFold monomer V2.0 prediction for integrator complex subunit 11 (Q5TA45) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 7BFP chain B against the predicted model Q5TA45: TM-score 0.94, RMSD 2.12 Å
- 5V8W chain F against the predicted model Q5TA45: TM-score 0.90, RMSD 1.48 Å
- 5V8W chain B against the predicted model Q5TA45: TM-score 0.89, RMSD 1.65 Å
- 5V8W chain D against the predicted model Q5TA45: TM-score 0.88, RMSD 1.59 Å
- 5V8W chain H against the predicted model Q5TA45: TM-score 0.86, RMSD 1.97 Å
- 7BFQ chain B against the predicted model Q5TA45: TM-score 0.84, RMSD 3.88 Å
- 7BFQ chain B against the predicted model Q5TA45: TM-score 0.84, RMSD 3.88 Å
- 7CUN chain K against the predicted model Q5TA45: TM-score 0.83, RMSD 3.78 Å
- 7CUN chain K against the predicted model Q5TA45: TM-score 0.83, RMSD 3.78 Å
Elsewhere
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