UniProt Q5T8I9
Small RNA 2'-O-methyltransferase (Q5T8I9)
Small RNA 2'-O-methyltransferase (UniProt Q5T8I9), EC 2.1.1.-: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q5T8I9
- Protein
- Small RNA 2'-O-methyltransferase
- EC
- 2.1.1.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
5 records of Q5T8I9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XCX | Methyltransferase domain of small RNA 2'-O-methyltransferase | x-ray diffraction | A | — | — |
| 4XCX | Methyltransferase domain of small RNA 2'-O-methyltransferase | x-ray diffraction | A | — | — |
| 5WY0 | Crystal structure of the methyltranferase domain of human HEN1 in complex with AdoMet | x-ray diffraction | A | SAM | 2 (best 0.46) |
| 5WY0 | Crystal structure of the methyltranferase domain of human HEN1 in complex with adomet | x-ray diffraction | A | — | — |
| Q5T8I9 | AlphaFold monomer V2.0 prediction for small RNA 2'-O-methyltransferase (Q5T8I9) | predicted | A | — | — |
Ligands
- SAM · S-adenosylmethionine · in 1 record
Experiment against prediction
- 4XCX chain A against the predicted model Q5T8I9: TM-score 0.98, RMSD 0.84 Å
- 4XCX chain A against the predicted model Q5T8I9: TM-score 0.98, RMSD 0.84 Å
- 5WY0 chain A against the predicted model Q5T8I9: TM-score 0.96, RMSD 1.48 Å
- 5WY0 chain A against the predicted model Q5T8I9: TM-score 0.96, RMSD 1.48 Å
Elsewhere
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