UniProt Q5T7N2

LINE-1 type transposase domain-containing protein 1 (Q5T7N2)

LINE-1 type transposase domain-containing protein 1 (UniProt Q5T7N2): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction…

UniProt: Q5T7N2
Protein: LINE-1 type transposase domain-containing protein 1
Experimental structures: 4
Predicted models: 1
Ligands: 2
Pockets: 15 · 5 records with a druggable one

Structures

5 records of Q5T7N2 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2LR6	NMR structure of a LINE-1 type transposase domain-containing protein 1 (L1TD1) from Homo sapiens	solution nmr	A, B	—	5 (best 0.51)
2LR6	NMR structure of a line-1 type transposase domain-containing protein 1 (L1TD1) from homo sapiens	solution nmr	A, B	—	5 (best 0.51)
3SOO	Crystal structure of a LINE-1 type transposase domain-containing protein 1 (L1TD1) from HOMO…	x-ray diffraction	A, B, C	SO4, CL	2 (best 0.69)
3SOO	Crystal structure of a line-1 type transposase domain-containing protein 1 (L1TD1) from homo…	x-ray diffraction	A, B, C	SO4, CL	2 (best 0.69)
Q5T7N2	AlphaFold monomer V2.0 prediction for line-1 type transposase domain- containing protein 1 (Q5T7N2)	predicted	A	—	1 (best 0.61)

Ligands

CL · Chloride ion · in 2 records
SO4 · Sulfate ion · in 2 records

Experiment against prediction

3SOO chain A against the predicted model Q5T7N2: TM-score 0.54, RMSD 2.68 Å
3SOO chain A against the predicted model Q5T7N2: TM-score 0.54, RMSD 2.68 Å
3SOO chain C against the predicted model Q5T7N2: TM-score 0.52, RMSD 2.83 Å
3SOO chain C against the predicted model Q5T7N2: TM-score 0.52, RMSD 2.83 Å
2LR6 chain A against the predicted model Q5T7N2: TM-score 0.50, RMSD 3.49 Å
2LR6 chain A against the predicted model Q5T7N2: TM-score 0.50, RMSD 3.49 Å

Elsewhere

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