UniProt Q5T1C6
Acyl-coenzyme a thioesterase THEM4 (Q5T1C6)
Acyl-coenzyme a thioesterase THEM4 (UniProt Q5T1C6): 4 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5T1C6
- Protein
- Acyl-coenzyme a thioesterase THEM4
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
5 records of Q5T1C6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4AE8 | Crystal structure of human THEM4 | x-ray diffraction | A, B, C, D | — | — |
| 4AE8 | Crystal structure of human THEM4 | x-ray diffraction | A, B, C, D | — | — |
| 4GAH | Human acyl-CoA thioesterases 4 in complex with undecan-2-one-CoA inhibitor | x-ray diffraction | A, B | — | — |
| 4GAH | Human acyl-CoA thioesterases 4 in complex with undecan-2-one-CoA inhibitor | x-ray diffraction | A, B | — | — |
| Q5T1C6 | AlphaFold monomer V2.0 prediction for acyl-coenzyme a thioesterase THEM4 (Q5T1C6) | predicted | A | — | 1 (best 0.71) |
Experiment against prediction
- 4GAH chain A against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.40 Å
- 4GAH chain A against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.40 Å
- 4AE8 chain A against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.39 Å
- 4AE8 chain A against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.39 Å
- 4AE8 chain D against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.39 Å
- 4AE8 chain D against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.39 Å
- 4AE8 chain B against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.43 Å
- 4AE8 chain B against the predicted model Q5T1C6: TM-score 0.99, RMSD 0.43 Å
- 4AE8 chain C against the predicted model Q5T1C6: TM-score 0.98, RMSD 0.69 Å
- 4AE8 chain C against the predicted model Q5T1C6: TM-score 0.98, RMSD 0.69 Å
Elsewhere
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