UniProt Q5SM01
Peptide chain release factor RF2 (Q5SM01)
Peptide chain release factor RF2 (UniProt Q5SM01): 6 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5SM01
- Protein
- Peptide chain release factor RF2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
7 records of Q5SM01 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IHR | RF2 of Thermus thermophilus | x-ray diffraction | 1 | — | — |
| 2IHR | RF2 of thermus thermophilus | x-ray diffraction | 1 | — | — |
| 4V4S | Crystal structure of the whole ribosomal complex. | x-ray diffraction | AY | — | — |
| 4V5E | Insights into translational termination from the structure of RF2 bound to the ribosome | x-ray diffraction | AY, CY | — | — |
| 4V5J | Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights… | x-ray diffraction | AY, CY | — | — |
| 5MDY | Structure of ArfA and TtRF2 bound to the 70S ribosome (pre-accommodated state) | electron microscopy | 7 | — | — |
| Q5SM01 | AlphaFold monomer V2.0 prediction for peptide chain release factor RF2 (Q5SM01) | predicted | A | — | 5 (best 0.65) |
Experiment against prediction
- 4V5J chain AY against the predicted model Q5SM01: TM-score 0.84, RMSD 3.45 Å
- 4V5E chain AY against the predicted model Q5SM01: TM-score 0.82, RMSD 3.82 Å
- 4V4S chain AY against the predicted model Q5SM01: TM-score 0.81, RMSD 3.74 Å
- 5MDY chain 7 against the predicted model Q5SM01: TM-score 0.72, RMSD 3.33 Å
- 2IHR chain 1 against the predicted model Q5SM01: TM-score 0.70, RMSD 3.13 Å
- 2IHR chain 1 against the predicted model Q5SM01: TM-score 0.70, RMSD 3.13 Å
Elsewhere
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