UniProt Q5SL04
Homoserine dehydrogenase (Q5SL04)
Homoserine dehydrogenase (UniProt Q5SL04), EC 1.1.1.3: 12 experimental structures on GenesisL1, 5 ligands bound, 28 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q5SL04
- Protein
- Homoserine dehydrogenase
- EC
- 1.1.1.3
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 28 · 5 records with a druggable one
Structures
12 records of Q5SL04 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EJW | Homoserine Dehydrogenase from Thermus thermophilus HB8 | x-ray diffraction | A, B, E, F | — | — |
| 2EJW | Homoserine dehydrogenase from thermus thermophilus HB8 | x-ray diffraction | A, B, E, F | — | — |
| 5XDF | Homoserine dehydrogenase from Thermus thermophilus HB8 complexed with HSE | x-ray diffraction | A, B | HSE, NA | 4 (best 0.74) |
| 5XDF | Homoserine dehydrogenase from thermus thermophilus HB8 complexed with hse | x-ray diffraction | A, B | HSE, NA | — |
| 6A0R | Homoserine dehydrogenase from Thermus thermophilus HB8 unliganded form | x-ray diffraction | B, A | NA, UNL | 5 (best 0.75) |
| 6A0R | Homoserine dehydrogenase from thermus thermophilus HB8 unliganded form | x-ray diffraction | B, A | NA, UNL | — |
| 6A0S | Homoserine dehydrogenase from Thermus thermophilus HB8 complexed with HSE and NADPH | x-ray diffraction | B, A | NA, HSE, NDP | 7 (best 0.74) |
| 6A0S | Homoserine dehydrogenase from thermus thermophilus HB8 complexed with hse and NADPH | x-ray diffraction | B, A | NA, HSE, NDP | — |
| 6A0T | Homoserine dehydrogenase K99A mutant from Thermus thermophilus HB8 complexed with HSE and NADP+ | x-ray diffraction | B, A | NA, HSE, NAP | 6 (best 0.79) |
| 6A0T | Homoserine dehydrogenase K99A mutant from thermus thermophilus HB8 complexed with hse and NADP+ | x-ray diffraction | B, A | NA, HSE, NAP | — |
| 6A0U | Homoserine dehydrogenase K195A mutant from Thermus thermophilus HB8 complexed with HSE and NADP+ | x-ray diffraction | B, A | NA, NAP, HSE, UNL | 6 (best 0.75) |
| 6A0U | Homoserine dehydrogenase K195A mutant from thermus thermophilus HB8 complexed with hse and NADP+ | x-ray diffraction | B, A | NA, NAP, HSE, UNL | — |
Ligands
Elsewhere
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