UniProt Q5SJC4
Crossover junction endodeoxyribonuclease RuvC (Q5SJC4)
Crossover junction endodeoxyribonuclease RuvC (UniProt Q5SJC4), EC 3.1.22.4: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q5SJC4
- Protein
- Crossover junction endodeoxyribonuclease RuvC
- EC
- 3.1.22.4
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 1 record with a druggable one
Structures
9 records of Q5SJC4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4EP4 | Thermus thermophilus RuvC structure | x-ray diffraction | A, B | — | — |
| 4EP4 | Thermus thermophilus ruvc structure | x-ray diffraction | A, B | — | — |
| 4EP5 | Thermus thermophilus RuvC structure | x-ray diffraction | A | — | — |
| 4EP5 | Thermus thermophilus ruvc structure | x-ray diffraction | A | — | — |
| 4LD0 | T. thermophilus RuvC in complex with Holliday junction substrate | x-ray diffraction | A, B | — | — |
| 4LD0 | T. thermophilus ruvc in complex with holliday junction substrate | x-ray diffraction | A, B | — | — |
| 6S16 | T. thermophilus RuvC in complex with Holliday junction substrate | x-ray diffraction | A, B | NA, CL | 6 (best 0.69) |
| 6S16 | T. thermophilus ruvc in complex with holliday junction substrate | x-ray diffraction | A, B | NA, CL | — |
| Q5SJC4 | AlphaFold monomer V2.0 prediction for crossover junction endodeoxyribonuclease ruvc (Q5SJC4) | predicted | A | — | 1 (best 0.46) |
Ligands
Experiment against prediction
- 4EP5 chain A against the predicted model Q5SJC4: TM-score 0.98, RMSD 0.71 Å
- 4EP5 chain A against the predicted model Q5SJC4: TM-score 0.98, RMSD 0.71 Å
- 4LD0 chain A against the predicted model Q5SJC4: TM-score 0.97, RMSD 1.02 Å
- 4LD0 chain A against the predicted model Q5SJC4: TM-score 0.97, RMSD 1.02 Å
- 4EP4 chain A against the predicted model Q5SJC4: TM-score 0.96, RMSD 1.13 Å
- 4EP4 chain A against the predicted model Q5SJC4: TM-score 0.96, RMSD 1.13 Å
- 6S16 chain B against the predicted model Q5SJC4: TM-score 0.96, RMSD 1.00 Å
- 6S16 chain B against the predicted model Q5SJC4: TM-score 0.96, RMSD 1.00 Å
- 4LD0 chain B against the predicted model Q5SJC4: TM-score 0.96, RMSD 1.02 Å
- 4LD0 chain B against the predicted model Q5SJC4: TM-score 0.96, RMSD 1.02 Å
Elsewhere
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