UniProt Q5S3G4
Cytochrome c oxidase subunit 5B, mitochondrial (Q5S3G4)
Cytochrome c oxidase subunit 5B, mitochondrial (UniProt Q5S3G4): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q5S3G4
- Protein
- Cytochrome c oxidase subunit 5B, mitochondrial
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 12 · 5 records with a druggable one
Structures
7 records of Q5S3G4 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8UGH | In-situ structure of typeA supercomplex with lipids in respiratory chain (composite) | electron microscopy | 4F | PEK, PGV, ZN | 1 (best 0.85) |
| 8UGI | High resolution in-situ structure of typeA supercomplex in respiratory chain (I1III2IV1,composite) | electron microscopy | 4F | PGV, ZN, PEK | 1 (best 0.86) |
| 8UGJ | In-situ structure of typeB supercomplex in respiratory chain (composite) | electron microscopy | 4F, 8F | PGV, ZN, PEK | 2 (best 0.85) |
| 8UGL | High resolution in-situ structure of complex IV in respiratory supercomplex | electron microscopy | 4F | PGV, ZN, PEK | 6 (best 0.86) |
| 8UGN | In-situ structure of typeO supercomplex in respiratory chain (composite) | electron microscopy | 4F, 8F | PGV, ZN, PEK | 2 (best 0.86) |
| 8UGR | In-situ structure of typeX supercomplex in respiratory chain (composite) | electron microscopy | 4F, 8F | PEK, ZN, PGV | — |
| Q5S3G4 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 5B, mitochondrial (Q5S3G4) | predicted | A | — | — |
Ligands
- PEK · (1S)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5E,8E,11E,14E)-icosa-5,8, 11,14-tetraenoate · in 6 records
- PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate · in 6 records
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 8UGH chain 4F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.22 Å
- 8UGJ chain 4F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.22 Å
- 8UGN chain 4F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.24 Å
- 8UGN chain 8F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.23 Å
- 8UGI chain 4F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.25 Å
- 8UGL chain 4F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.25 Å
- 8UGJ chain 8F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.23 Å
- 8UGR chain 8F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.26 Å
- 8UGR chain 4F against the predicted model Q5S3G4: TM-score 0.93, RMSD 1.25 Å
Elsewhere
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