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UniProt Q5NGA7

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (Q5NGA7)

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (UniProt Q5NGA7): 3 experimental structures on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q5NGA7
Protein
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Experimental structures
3
Predicted models
0
Ligands
2
Pockets
6 · 1 record with a druggable one

Structures

3 records of Q5NGA7 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4PZVCrystal structure of Francisella tularensis HPPK-DHPS in complex with bisubstrate analog HPPK…x-ray diffractionA——
4PZVCrystal structure of francisella tularensis hppk-dhps in complex with bisubstrate analog hppk…x-ray diffractionA——
8SL9Crystal structure of Francisella tularensis HPPK-DHPS in complex with HPPK inhibitor HP-73x-ray diffractionAH73, CL6 (best 0.62)

Ligands

  • CL · Chloride ion · in 1 record
  • H73 · 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7, 8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine · in 1 record

Elsewhere

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