UniProt Q5JUK3
Potassium channel subfamily T member 1 (Q5JUK3)
Potassium channel subfamily T member 1 (UniProt Q5JUK3): 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 134 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5JUK3
- Protein
- Potassium channel subfamily T member 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 134 · 7 records with a druggable one
Structures
7 records of Q5JUK3 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8HIR | potassium channels | electron microscopy | A, B, C, D | NA, K, 6OU, ZN | 20 (best 0.82) |
| 8HK6 | potassium channel | electron microscopy | A, B, C, D | K, ZN | 20 (best 0.83) |
| 8HKF | ion channel | electron microscopy | A, B, C, D | ZN, K | 20 (best 0.82) |
| 8HKK | ion channel | electron microscopy | A, B, C, D | ZN, NA, K | 20 (best 0.84) |
| 8HKM | ion channel | electron microscopy | A, B, C, D | K, ZN, 6OU | 20 (best 0.83) |
| 8HKQ | ion channel | electron microscopy | D, A, C, B | LQ9, ZN, K, NA | 20 (best 0.85) |
| Q5JUK3 | AlphaFold monomer V2.0 prediction for potassium channel subfamily T member 1 (Q5JUK3) | predicted | A | — | 14 (best 0.71) |
Ligands
- K · Potassium ion · in 6 records
- ZN · Zinc ion · in 6 records
- NA · Sodium ion · in 3 records
- 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · in 2 records
- LQ9 · ~{N}-[(1~{S})-1-[3-(2-methoxypyridin-4-yl)-1,2,4-oxadiazol-5-yl]ethyl]-2-methyl-5-(trifluoromethyl)pyrazole-3-carboxamide · in 1 record
Experiment against prediction
- 8HIR chain A against the predicted model Q5JUK3: TM-score 0.97, RMSD 1.83 Å
- 8HKK chain A against the predicted model Q5JUK3: TM-score 0.93, RMSD 2.74 Å
- 8HKF chain A against the predicted model Q5JUK3: TM-score 0.91, RMSD 3.16 Å
- 8HKQ chain D against the predicted model Q5JUK3: TM-score 0.90, RMSD 3.27 Å
- 8HK6 chain A against the predicted model Q5JUK3: TM-score 0.88, RMSD 4.07 Å
- 8HKM chain A against the predicted model Q5JUK3: TM-score 0.87, RMSD 4.16 Å
Elsewhere
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