UniProt Q5J8M3
ER membrane protein complex subunit 4 (Q5J8M3)
ER membrane protein complex subunit 4 (UniProt Q5J8M3): 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5J8M3
- Protein
- ER membrane protein complex subunit 4
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 42 · 7 records with a druggable one
Structures
12 records of Q5J8M3 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6Z3W | Human ER membrane protein complex | electron microscopy | D | — | — |
| 6Z3W | Human er membrane protein complex | electron microscopy | D | — | — |
| 7ADO | Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs | electron microscopy | D | NAG | 6 (best 0.79) |
| 7ADO | Cryo-EM structure of human er membrane protein complex in lipid nanodiscs | electron microscopy | D | NAG | — |
| 7ADP | Cryo-EM structure of human ER membrane protein complex in GDN detergent | electron microscopy | D | — | 6 (best 0.80) |
| 7ADP | Cryo-EM structure of human er membrane protein complex in gdn detergent | electron microscopy | D | — | — |
| 8EOI | Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | electron microscopy | D | — | 3 (best 0.75) |
| 8J0N | cryo-EM structure of human EMC | electron microscopy | D | — | 6 (best 0.84) |
| 8J0O | cryo-EM structure of human EMC and VDAC | electron microscopy | D | — | 9 (best 0.80) |
| 8S9S | Structure of the human ER membrane protein complex (EMC) in GDN | electron microscopy | 4 | PCW | 8 (best 0.79) |
| 9C7V | Structure of the human BOS:human EMC complex in GDN | electron microscopy | 4 | — | 4 (best 0.75) |
| Q5J8M3 | AlphaFold monomer V2.0 prediction for er membrane protein complex subunit 4 (Q5J8M3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8J0O chain D against the predicted model Q5J8M3: TM-score 0.69, RMSD 2.70 Å
- 8J0N chain D against the predicted model Q5J8M3: TM-score 0.69, RMSD 2.68 Å
- 6Z3W chain D against the predicted model Q5J8M3: TM-score 0.68, RMSD 2.47 Å
- 6Z3W chain D against the predicted model Q5J8M3: TM-score 0.68, RMSD 2.47 Å
- 9C7V chain 4 against the predicted model Q5J8M3: TM-score 0.60, RMSD 3.35 Å
- 8S9S chain 4 against the predicted model Q5J8M3: TM-score 0.60, RMSD 3.38 Å
- 7ADO chain D against the predicted model Q5J8M3: TM-score 0.38, RMSD 3.12 Å
- 7ADO chain D against the predicted model Q5J8M3: TM-score 0.38, RMSD 3.12 Å
- 8EOI chain D against the predicted model Q5J8M3: TM-score 0.29, RMSD 2.00 Å
- 7ADP chain D against the predicted model Q5J8M3: TM-score 0.28, RMSD 2.34 Å
Elsewhere
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