UniProt Q5F4S7
Transient receptor potential cation channel, subfamily M, member 3 (Q5F4S7)
Transient receptor potential cation channel, subfamily M, member 3 (UniProt Q5F4S7): 12 experimental structures on GenesisL1, 4 ligands bound, 201 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q5F4S7
- Protein
- Transient receptor potential cation channel, subfamily M, member 3
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 201 · 11 records with a druggable one
Structures
12 records of Q5F4S7 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RMV | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | x-ray diffraction | C | — | 1 (best 0.80) |
| 6RMV | The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer | x-ray diffraction | C | — | — |
| 8DDQ | cryo-EM structure of TRPM3 ion channel in the presence of soluble Gbg, focused on channel | electron microscopy | A, B, C, D | 3PH, 9Z9, NA | 20 (best 0.87) |
| 8DDR | cryo-EM structure of TRPM3 ion channel in the absence of PIP2 | electron microscopy | A, B, C, D | 3PH, 9Z9, NA | 20 (best 0.87) |
| 8DDS | cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state1 | electron microscopy | A, B, C, D | 3PH, 9Z9, PIO, NA | 20 (best 0.88) |
| 8DDT | cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state2 | electron microscopy | A, B, C, D | 3PH, 9Z9, PIO, NA | 20 (best 0.88) |
| 8DDV | Cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state4 | electron microscopy | A, B, C, D | 3PH, 9Z9, PIO, NA | 20 (best 0.89) |
| 8DDW | cryo-EM structure of TRPM3 ion channel in complex with Gbg, tethered by ALFA-nanobody | electron microscopy | A, B, C, D | — | 20 (best 0.83) |
| 8DDX | cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by… | electron microscopy | A, B, C, D | 3PH, PIO, 9Z9, NA | 20 (best 0.87) |
| 8ED7 | cryo-EM structure of TRPM3 ion channel in apo state | electron microscopy | A, B, C, D | 9Z9 | 20 (best 0.87) |
| 8ED8 | cryo-EM structure of TRPM3 ion channel in the presence of PIP2 and PregS, state 1 | electron microscopy | A, B, C, D | 3PH, 9Z9, PIO | 20 (best 0.87) |
| 8ED9 | cryo-EM structure of TRPM3 ion channel in the presence with PIP2 and PregS, state 2 | electron microscopy | A, B, C, D | 3PH, 9Z9, PIO | 20 (best 0.86) |
Ligands
- 9Z9 · (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en · in 9 records
- 3PH · 1,2-diacyl-glycerol-3-sn-phosphate · in 8 records
- NA · Sodium ion · in 6 records
- PIO · [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2, 3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate · in 6 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.