UniProt Q5CR27
Lysine--tRNA ligase (Q5CR27)
Lysine--tRNA ligase (UniProt Q5CR27), EC 6.1.1.6: 12 experimental structures on GenesisL1, 10 ligands bound, 53 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q5CR27
- Protein
- Lysine--tRNA ligase
- EC
- 6.1.1.6
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 53 · 4 records with a druggable one
Structures
12 records of Q5CR27 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ELN | Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine | x-ray diffraction | A, B, C, D | — | — |
| 5ELN | Crystal structure of lysyl-tRNA synthetase from cryptosporidium parvum complexed with L-lysine | x-ray diffraction | A, B, C, D | — | — |
| 5ELO | Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and… | x-ray diffraction | A, B, C, D | KRS, SO4 | — |
| 5ELO | Crystal structure of lysyl-tRNA synthetase from cryptosporidium parvum complexed with L-lysine and… | x-ray diffraction | A, B, C, D | — | — |
| 6BNI | Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and… | x-ray diffraction | A, B | LYS, ADN, SO4, NA | 12 (best 0.81) |
| 6BNI | Crystal structure of lysyl-tRNA synthetase from cryptosporidium parvum complexed with L-lysine and… | x-ray diffraction | A, B | ADN, SO4, NA | — |
| 6C86 | Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with… | x-ray diffraction | A, B | KAA, NA, SO4, CL | 12 (best 0.82) |
| 6C86 | Crystal structure of lysyl-tRNA synthetase from cryptosporidium parvum complexed with… | x-ray diffraction | A, B | NA, SO4, CL | — |
| 6HCW | Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and… | x-ray diffraction | A, B | FYB | — |
| 6HCW | Crystal structure of lysyl-tRNA synthetase from cryptosporidium parvum complexed with L-lysine and… | x-ray diffraction | A, B | FYB | — |
| 7ZOG | Crystal structure of Cryptosporidium parvum -Plasmodium falciparum mutant lysyl tRNA synthetase in… | x-ray diffraction | A, B, C, D | LYS, JE5 | 20 (best 0.85) |
| 8S00 | CpKRS complexed with lysine and an inhibitor | x-ray diffraction | A, B | A1H4W, LYS | 9 (best 0.82) |
Ligands
- SO4 · Sulfate ion · in 5 records
- NA · Sodium ion · in 4 records
- LYS · Lysine · in 3 records
- ADN · Adenosine · in 2 records
- CL · Chloride ion · in 2 records
- FYB · ~{N}-[[4,4-bis(fluoranyl)-1-oxidanyl-cyclohexyl]methyl]-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide · in 2 records
- A1H4W · 6-oxidanyl-~{N}-[(1-oxidanylcyclohexyl)methyl]-4-oxidanylidene-chromene-2-carboxamide · in 1 record
- JE5 · 8-[[4-[2-[2-[2-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]sulfonylamino]-~{N}-(cyclohexylmethyl)-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide · in 1 record
- KAA · 5'-O-[(L-lysylamino)sulfonyl]adenosine · in 1 record
- KRS · cladosporin · in 1 record
Elsewhere
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