UniProt Q59EX4
Phospholipid-transporting ATPase (Q59EX4)
Phospholipid-transporting ATPase (UniProt Q59EX4), EC 7.6.2.1: 14 experimental structures on GenesisL1, 8 ligands bound, 51 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q59EX4
- Protein
- Phospholipid-transporting ATPase
- EC
- 7.6.2.1
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 51 · 4 records with a druggable one
Structures
14 records of Q59EX4 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K7G | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class1) | electron microscopy | A | NAG, Y01 | — |
| 6K7G | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state CLASS1) | electron microscopy | A | NAG, Y01 | — |
| 6K7H | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class2) | electron microscopy | A | NAG, Y01 | 13 (best 0.77) |
| 6K7H | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state CLASS2) | electron microscopy | A | NAG, Y01 | — |
| 6K7I | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class2) | electron microscopy | A | NAG, ACP, Y01 | 12 (best 0.79) |
| 6K7I | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state CLASS2) | electron microscopy | A | NAG, ACP, Y01 | — |
| 6K7J | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class1) | electron microscopy | A | NAG, ACP, MG, Y01 | 14 (best 0.78) |
| 6K7J | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state CLASS1) | electron microscopy | A | NAG, ACP, MG, Y01 | — |
| 6K7K | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ADP-Pi state) | electron microscopy | A | NAG, ADP, ALF, MG, Y01 | — |
| 6K7K | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ADP- pi state) | electron microscopy | A | NAG, ADP, ALF, MG, Y01 | — |
| 6K7L | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2P state CLASS2) | electron microscopy | A | NAG, BEF, MG, Y01 | — |
| 6K7M | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2Pi-PL state) | electron microscopy | A | NAG, ALF, Y01, MG, D39 | 12 (best 0.83) |
| 6K7M | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2PI-pl state) | electron microscopy | A | NAG, ALF, Y01, MG, D39 | — |
| 6K7N | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1P state) | electron microscopy | A | NAG, ALF, Y01, MG | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 14 records
- Y01 · Cholesterol hemisuccinate · in 14 records
- MG · Magnesium ion · in 8 records
- ALF · Tetrafluoroaluminate ion · in 5 records
- ACP · Phosphomethylphosphonic acid adenylate ester · in 4 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- D39 · (2~{S})-2-azanyl-3-[[(2~{R})-3-hexadecanoyloxy-2-[(~{Z})-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid · in 2 records
- BEF · Beryllium trifluoride ion · in 1 record
Elsewhere
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