UniProt Q59819
Cytochrome P-450 (Q59819)
Cytochrome P-450 (UniProt Q59819): 14 experimental structures on GenesisL1, 6 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q59819
- Protein
- Cytochrome P-450
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 20 · 1 record with a druggable one
Structures
14 records of Q59819 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XE3 | OleP, the cytochrome P450 epoxidase from Streptomyces antibioticus involved in Oleandomycin… | x-ray diffraction | A, B | — | — |
| 4XE3 | Olep, the cytochrome P450 epoxidase from streptomyces antibioticus involved in oleandomycin… | x-ray diffraction | A, B | — | — |
| 5MNS | Structural and functional characterization of olep in complex with 6DEB in sodium formate | x-ray diffraction | A, B, C, D, E, F | HEM, DEB | — |
| 5MNV | Structural and functional characterization of olep in complex with 6DEB in peg | x-ray diffraction | A, B, C, D, E, F, G, H, I | HEM, DEB | — |
| 6ZHZ | OleP-oleandolide(DEO) in high salt crystallization conditions | x-ray diffraction | A, B, C, D, E, F | HEM, QR8, NA | — |
| 6ZHZ | Olep-OLEANDOLIDE(DEO) in high salt crystallization conditions | x-ray diffraction | A, B, C, D, E, F | HEM, QR8, NA | — |
| 6ZI2 | OleP-oleandolide(DEO) in low salt crystallization conditions | x-ray diffraction | A, B, C, D, E, F, G, H, I | HEM, QR8 | — |
| 6ZI2 | Olep-OLEANDOLIDE(DEO) in low salt crystallization conditions | x-ray diffraction | A, B, C, D, E, F, G, H, I | HEM, QR8 | — |
| 6ZI3 | Crystal structure of olep-6DEB bound to L-rhamnose | x-ray diffraction | A, B, C, D, E, F | HEM, DEB, RAM, NA | — |
| 6ZI7 | Crystal structure of olep-OLEANDOLIDE(DEO) bound to L-rhamnose | x-ray diffraction | A, B, C, D, E, F | HEM, QR8, RAM, NA | — |
| 7Q6R | Olep mutant E89Y in complex with 6DEB | x-ray diffraction | A, B, C, D, E, F | HEM, DEB | — |
| 7Q6X | Olep mutant S240Y in complex with 6DEB | x-ray diffraction | A, B, C, D, E, F | HEM, DEB | — |
| 7Q89 | Olep mutant G92W in complex with 6DEB | x-ray diffraction | A, B, C, D, E, F | HEM, DEB, NA | — |
| 8QYI | OleP in complex with lithocholic acid in high salt crystallization conditions | x-ray diffraction | A, B, C, D, E, F | HEM, 4OA, NA | 20 (best 0.87) |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 12 records
- DEB · 6-deoxyerythronolide B · in 6 records
- NA · Sodium ion · in 6 records
- QR8 · (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S}, 13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione · in 5 records
- RAM · alpha-L-rhamnopyranose · in 2 records
- 4OA · (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid · in 1 record
Elsewhere
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