UniProt Q58380
Sirohydrochlorin cobaltochelatase (Q58380)
Sirohydrochlorin cobaltochelatase (UniProt Q58380), EC 4.99.1.11, 4.99.1.3: 19 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q58380
- Protein
- Sirohydrochlorin cobaltochelatase
- EC
- 4.99.1.11, 4.99.1.3
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 2 · 2 records with a druggable one
Structures
20 records of Q58380 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6M25 | Sirohydrochlorin nickelochelatase CfbA in P41 space group | x-ray diffraction | A, B | — | — |
| 6M25 | Sirohydrochlorin nickelochelatase cfba in P41 space group | x-ray diffraction | A, B | — | — |
| 6M26 | Sirohydrochlorin nickelochelatase CfbA in P212121 space group | x-ray diffraction | A, B | — | — |
| 6M26 | Sirohydrochlorin nickelochelatase cfba in P212121 space group | x-ray diffraction | A, B | — | — |
| 6M27 | Sirohydrochlorin nickelochelatase CfbA in complex with Ni2+ | x-ray diffraction | A, B | NI | — |
| 6M27 | Sirohydrochlorin nickelochelatase cfba in complex with NI2+ | x-ray diffraction | A, B | NI | — |
| 6M28 | Sirohydrochlorin nickelochelatase CfbA in complex with Co2+ | x-ray diffraction | A, B | CO | — |
| 6M28 | Sirohydrochlorin nickelochelatase cfba in complex with CO2+ | x-ray diffraction | A, B | CO | — |
| 6M29 | Sirohydrochlorin nickelochelatase CfbA in complex with Co2+ and formate | x-ray diffraction | A, B | CO | — |
| 6M29 | Sirohydrochlorin nickelochelatase cfba in complex with CO2+ and formate | x-ray diffraction | A, B | CO | — |
| 6M2A | A non-His-rich type of chimeric sirohydrochlorin nickelochelatase CfbA from M. jannaschii and M.… | x-ray diffraction | A, B | SO4 | — |
| 6M2A | A non-his-rich type of chimeric sirohydrochlorin nickelochelatase cfba from M. jannaschii and M.… | x-ray diffraction | A, B | SO4 | — |
| 6M2E | Sirohydrochlorin nickelochelatase cfba in complex with sirohydrochlorin | x-ray diffraction | A, B | SHN | — |
| 6M2F | Sirohydrochlorin nickelochelatase cfba in complex with nickel- sirohydrochlorin | x-ray diffraction | A, B | F0L | — |
| 6M2G | Sirohydrochlorin nickelochelatase CfbA in complex with cobalt-sirohydrochlorin | x-ray diffraction | A, B | F0X | — |
| 6M2G | Sirohydrochlorin nickelochelatase cfba in complex with cobalt- sirohydrochlorin | x-ray diffraction | A, B | F0X | — |
| 6M2H | A reaction intermediate of sirohydrochlorin nickelochelatase cfba in complex with NI2+ and… | x-ray diffraction | A, B | NI, SHN | — |
| 8I55 | Wild-type CfbA at 1.99 angstrom resolution | x-ray diffraction | A, B | — | 1 (best 0.76) |
| 8IYU | CfbA S11T variant with Ni(II) ions | x-ray diffraction | A, B | NI | 1 (best 0.76) |
| Q58380 | AlphaFold monomer V2.0 prediction for sirohydrochlorin cobaltochelatase (Q58380) | predicted | A | — | — |
Ligands
- CO · Cobalt (II) ion · in 4 records
- NI · Nickel (II) ion · in 4 records
- F0X · cobalt-sirohydrochlorin · in 2 records
- SHN · 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13-tetrahydroporphyrin-2,7,12,18-tetrayl]tetrapropanoic acid · in 2 records
- SO4 · Sulfate ion · in 2 records
- F0L · Nickel-sirohydrochlorin · in 1 record
Experiment against prediction
- 8IYU chain A against the predicted model Q58380: TM-score 0.99, RMSD 0.37 Å
- 8I55 chain A against the predicted model Q58380: TM-score 0.99, RMSD 0.37 Å
- 8IYU chain B against the predicted model Q58380: TM-score 0.99, RMSD 0.40 Å
- 6M28 chain B against the predicted model Q58380: TM-score 0.99, RMSD 0.41 Å
- 6M28 chain B against the predicted model Q58380: TM-score 0.99, RMSD 0.41 Å
- 8I55 chain B against the predicted model Q58380: TM-score 0.99, RMSD 0.42 Å
- 6M28 chain A against the predicted model Q58380: TM-score 0.99, RMSD 0.43 Å
- 6M28 chain A against the predicted model Q58380: TM-score 0.99, RMSD 0.43 Å
- 6M2G chain A against the predicted model Q58380: TM-score 0.99, RMSD 0.46 Å
- 6M2G chain A against the predicted model Q58380: TM-score 0.99, RMSD 0.46 Å
Elsewhere
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