UniProt Q57727
Digeranylgeranylglyceryl phosphate synthase (Q57727)
Digeranylgeranylglyceryl phosphate synthase (UniProt Q57727), EC 2.5.1.42: 5 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q57727
- Protein
- Digeranylgeranylglyceryl phosphate synthase
- EC
- 2.5.1.42
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 8 · 2 records with a druggable one
Structures
6 records of Q57727 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6M31 | Structural and Functional Insights into an Archaeal Lipid Synthase | x-ray diffraction | A, B | PO4, MG, MPG | 4 (best 0.71) |
| 6M31 | Structural and functional insights into an archaeal lipid synthase | x-ray diffraction | A, B | PO4, MG, MPG | — |
| 6M34 | Structural and functional insights into an Archaeal synthase | x-ray diffraction | A, B | MPG, DMA, PO4, MG | 4 (best 0.70) |
| 6M34 | Structural and functional insights into an archaeal synthase | x-ray diffraction | A, B | MPG, DMA, PO4, MG | — |
| 7BPU | Structural and mechanistic insights into the biosynthesis of digeranylgeranylglyceryl phosphate… | x-ray diffraction | A, B | PO4 | — |
| Q57727 | AlphaFold monomer V2.0 prediction for digeranylgeranylglyceryl phosphate synthase (Q57727) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6M31 chain B against the predicted model Q57727: TM-score 0.92, RMSD 1.94 Å
- 6M31 chain B against the predicted model Q57727: TM-score 0.92, RMSD 1.94 Å
- 6M34 chain A against the predicted model Q57727: TM-score 0.91, RMSD 1.99 Å
- 6M34 chain A against the predicted model Q57727: TM-score 0.91, RMSD 1.99 Å
- 7BPU chain A against the predicted model Q57727: TM-score 0.91, RMSD 1.99 Å
- 6M31 chain A against the predicted model Q57727: TM-score 0.91, RMSD 2.03 Å
- 6M31 chain A against the predicted model Q57727: TM-score 0.91, RMSD 2.03 Å
- 6M34 chain B against the predicted model Q57727: TM-score 0.91, RMSD 2.03 Å
- 6M34 chain B against the predicted model Q57727: TM-score 0.91, RMSD 2.03 Å
- 7BPU chain B against the predicted model Q57727: TM-score 0.91, RMSD 2.03 Å
Elsewhere
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