UniProt Q56218
NADH-quinone oxidoreductase subunit 6 (Q56218)
NADH-quinone oxidoreductase subunit 6 (UniProt Q56218), EC 1.6.5.11, 7.1.1.-: 33 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 21 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q56218
- Protein
- NADH-quinone oxidoreductase subunit 6
- EC
- 1.6.5.11, 7.1.1.-
- Experimental structures
- 33
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 21 · 7 records with a druggable one
Structures
34 records of Q56218 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FUG | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus | x-ray diffraction | 6, F, O, X | — | — |
| 2FUG | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus | x-ray diffraction | 6, F, O, X | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | electron microscopy | 6 | — | — |
| 2YBB | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (emd-1876) | electron microscopy | 6 | — | — |
| 3I9V | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus… | x-ray diffraction | 6, F | — | — |
| 3I9V | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus… | x-ray diffraction | 6, F | — | — |
| 3IAM | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus… | x-ray diffraction | 6, F | — | — |
| 3IAM | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus… | x-ray diffraction | 6, F | — | — |
| 3IAS | Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus… | x-ray diffraction | 6, F, O, X | — | — |
| 3IAS | Crystal structure of the hydrophilic domain of respiratory complex I from thermus thermophilus… | x-ray diffraction | 6, F, O, X | — | — |
| 3M9S | Crystal structure of respiratory complex I from Thermus thermophilus | x-ray diffraction | 6, F | — | — |
| 3M9S | Crystal structure of respiratory complex I from thermus thermophilus | x-ray diffraction | 6, F | — | — |
| 4HEA | Crystal structure of the entire respiratory complex I from Thermus thermophilus | x-ray diffraction | 6, G | — | — |
| 4HEA | Crystal structure of the entire respiratory complex I from thermus thermophilus | x-ray diffraction | 6, G | — | — |
| 6I0D | Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiqui | x-ray diffraction | 6, G | DCQ, SF4 | — |
| 6I0D | Respiratory complex I from thermus thermophilus with bound decyl- ubiquinone | x-ray diffraction | 6, G | DCQ, SF4 | — |
| 6I1P | Respiratory complex I from Thermus thermophilus with bound NADH | x-ray diffraction | 6, G | SF4 | — |
| 6I1P | Respiratory complex I from thermus thermophilus with bound NADH | x-ray diffraction | 6, G | SF4 | — |
| 6Q8O | Respiratory complex I from Thermus thermophilus with bound Piericidin A | x-ray diffraction | 6, G | HQH, SF4 | 3 (best 0.88) |
| 6Q8O | Respiratory complex I from thermus thermophilus with bound piericidin a | x-ray diffraction | 6, G | HQH, SF4 | — |
| 6Q8W | Respiratory complex I from thermus thermophilus with bound aureothin. | x-ray diffraction | 6, G | HQW, SF4 | — |
| 6Q8X | Respiratory complex I from Thermus thermophilus with bound Pyridaben. | x-ray diffraction | 6, G | HQK, SF4 | 3 (best 0.87) |
| 6Q8X | Respiratory complex I from thermus thermophilus with bound pyridaben. | x-ray diffraction | 6, G | HQK, SF4 | — |
| 6Y11 | Respiratory complex I from Thermus thermophilus | x-ray diffraction | 6, G | SF4 | 3 (best 0.88) |
| 6Y11 | Respiratory complex I from thermus thermophilus | x-ray diffraction | 6, G | SF4 | — |
| 6ZIY | Respiratory complex I from Thermus thermophilus, NADH dataset, major state | electron microscopy | 6 | SF4 | 2 (best 0.88) |
| 6ZIY | Respiratory complex I from thermus thermophilus, NADH dataset, major state | electron microscopy | 6 | SF4 | — |
| 6ZJL | Respiratory complex I from Thermus thermophilus, NAD+ dataset, major state | electron microscopy | 6 | SF4 | 2 (best 0.87) |
| 6ZJL | Respiratory complex I from thermus thermophilus, NAD+ dataset, major state | electron microscopy | 6 | SF4 | — |
| 6ZJN | Respiratory complex I from Thermus thermophilus, NADH dataset, minor state | electron microscopy | 6 | SF4 | 5 (best 0.85) |
| 6ZJN | Respiratory complex I from thermus thermophilus, NADH dataset, minor state | electron microscopy | 6 | SF4 | — |
| 6ZJY | Respiratory complex I from Thermus thermophilus, NAD+ dataset, minor state | electron microscopy | 6 | SF4 | 2 (best 0.83) |
| 6ZJY | Respiratory complex I from thermus thermophilus, NAD+ dataset, minor state | electron microscopy | 6 | SF4 | — |
| Q56218 | AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit 6 (Q56218) | predicted | A | — | 1 (best 0.35) |
Ligands
Experiment against prediction
- 6I0D chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.67 Å
- 6I0D chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.67 Å
- 6Q8W chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.66 Å
- 6Y11 chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.67 Å
- 6Y11 chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.67 Å
- 3IAS chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.90 Å
- 3IAS chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.90 Å
- 6Q8O chain G against the predicted model Q56218: TM-score 0.91, RMSD 1.70 Å
- 3M9S chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.70 Å
- 3M9S chain 6 against the predicted model Q56218: TM-score 0.91, RMSD 1.70 Å
Elsewhere
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