UniProt Q55080
Cytochrome P450 CYP119 (Q55080)
Cytochrome P450 CYP119 (UniProt Q55080), EC 1.14.14.-: 18 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q55080
- Protein
- Cytochrome P450 CYP119
- EC
- 1.14.14.-
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 44 · 5 records with a druggable one
Structures
19 records of Q55080 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F4T | Thermophilic P450: CYP119 from sulfolobus solfactaricus with 4-phenylimidazole bound | x-ray diffraction | A, B | ZN, SO4, HEM, PIM | 10 (best 0.87) |
| 1F4T | Thermophilic P450: CYP119 from sulfolobus solfactaricus with 4- phenylimidazole bound | x-ray diffraction | A, B | — | — |
| 1F4U | Thermophilic P450: CYP119 from sulfolobus solfactaricus | x-ray diffraction | A, B | SO4, HEM | 10 (best 0.84) |
| 1F4U | Thermophilic P450: CYP119 from sulfolobus solfactaricus | x-ray diffraction | A, B | — | — |
| 1IO7 | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: high resolution structural… | x-ray diffraction | A, B | HEM | 8 (best 0.81) |
| 1IO7 | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: high resolution structural… | x-ray diffraction | A, B | — | — |
| 1IO8 | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: High resolution structural… | x-ray diffraction | A, B | HEM | 8 (best 0.82) |
| 1IO8 | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: high resolution structural… | x-ray diffraction | A, B | — | — |
| 1IO9 | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: high resolution structural… | x-ray diffraction | A, B | HEM | 8 (best 0.82) |
| 1IO9 | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: high resolution structural… | x-ray diffraction | A, B | — | — |
| 4TT5 | Crystal Structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-bromophenyl)-1H… | x-ray diffraction | A | — | — |
| 4TT5 | Crystal structure of CYP119 from sulfolobus acidocaldarius, complexed with 4-(4-bromophenyl)-1H… | x-ray diffraction | A | — | — |
| 4TUV | X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with… | x-ray diffraction | A | — | — |
| 4TUV | X-ray crystal structure of CYP119 from sulfolobus acidocaldarius, complexed with… | x-ray diffraction | A | — | — |
| 4WPD | X-ray Crystal Structure of CYP119 complexed with 4-(4-flourophenyl)-1H-imidazole | x-ray diffraction | A, B | — | — |
| 4WPD | X-ray crystal structure of CYP119 complexed with 4-(4-flourophenyl)- 1H-imidazole | x-ray diffraction | A, B | — | — |
| 4WQJ | Crystal Structure of CYP119 from Sulfolobus acidocaldarius, Collected at 298K and Complexed with… | x-ray diffraction | A | — | — |
| 4WQJ | Crystal structure of CYP119 from sulfolobus acidocaldarius, collected at 298K and complexed with… | x-ray diffraction | A | — | — |
| Q55080 | AlphaFold monomer V2.0 prediction for cytochrome P450 119 (Q55080) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1IO9 chain B against the predicted model Q55080: TM-score 0.99, RMSD 0.87 Å
- 1IO9 chain B against the predicted model Q55080: TM-score 0.99, RMSD 0.87 Å
- 1IO7 chain B against the predicted model Q55080: TM-score 0.99, RMSD 0.97 Å
- 1IO7 chain B against the predicted model Q55080: TM-score 0.99, RMSD 0.97 Å
- 1IO8 chain B against the predicted model Q55080: TM-score 0.99, RMSD 0.98 Å
- 1IO8 chain B against the predicted model Q55080: TM-score 0.99, RMSD 0.98 Å
- 1IO9 chain A against the predicted model Q55080: TM-score 0.98, RMSD 1.19 Å
- 1IO9 chain A against the predicted model Q55080: TM-score 0.98, RMSD 1.19 Å
- 1F4T chain A against the predicted model Q55080: TM-score 0.98, RMSD 1.05 Å
- 1F4T chain A against the predicted model Q55080: TM-score 0.98, RMSD 1.05 Å
Elsewhere
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