UniProt Q54XS1
Phenylalanine-4-hydroxylase (Q54XS1)
Phenylalanine-4-hydroxylase (UniProt Q54XS1), EC 1.14.16.1, 1.14.16.4: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 82 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q54XS1
- Protein
- Phenylalanine-4-hydroxylase
- EC
- 1.14.16.1, 1.14.16.4
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 82 · 7 records with a druggable one
Structures
7 records of Q54XS1 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5JK5 | Phenylalanine hydroxylase from dictyostelium - BH2 complex | x-ray diffraction | A, B | FE, PIN, HBI | 13 (best 0.79) |
| 5JK5 | Phenylalanine hydroxylase from dictyostelium - BH2 complex | x-ray diffraction | A, B | FE, PIN, HBI | 13 (best 0.79) |
| 5JK6 | Phenylalanine hydroxylase from dictyostelium - apo form | x-ray diffraction | A, B | PIN, FE | 14 (best 0.73) |
| 5JK6 | Phenylalanine hydroxylase from dictyostelium - apo form | x-ray diffraction | A, B | PIN, FE | 14 (best 0.73) |
| 5JK8 | Phenylalanine hydroxylase from dictyostelium - BH2, norleucine complex | x-ray diffraction | A, B | PIN, HBI, FE, NLE | 11 (best 0.74) |
| 5JK8 | Phenylalanine hydroxylase from dictyostelium - BH2, norleucine complex | x-ray diffraction | A, B | PIN, HBI, FE, NLE | 11 (best 0.74) |
| Q54XS1 | AlphaFold monomer V2.0 prediction for phenylalanine-4-hydroxylase (Q54XS1) | predicted | A | — | 6 (best 0.75) |
Ligands
Experiment against prediction
- 5JK5 chain A against the predicted model Q54XS1: TM-score 1.00, RMSD 0.47 Å
- 5JK5 chain A against the predicted model Q54XS1: TM-score 1.00, RMSD 0.47 Å
- 5JK6 chain A against the predicted model Q54XS1: TM-score 1.00, RMSD 0.49 Å
- 5JK6 chain A against the predicted model Q54XS1: TM-score 1.00, RMSD 0.49 Å
- 5JK8 chain A against the predicted model Q54XS1: TM-score 0.99, RMSD 0.62 Å
- 5JK8 chain A against the predicted model Q54XS1: TM-score 0.99, RMSD 0.62 Å
- 5JK8 chain B against the predicted model Q54XS1: TM-score 0.99, RMSD 0.87 Å
- 5JK8 chain B against the predicted model Q54XS1: TM-score 0.99, RMSD 0.87 Å
- 5JK5 chain B against the predicted model Q54XS1: TM-score 0.99, RMSD 0.99 Å
- 5JK5 chain B against the predicted model Q54XS1: TM-score 0.99, RMSD 0.99 Å
Elsewhere
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