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Ligand · NLE

NLE · Norleucine

NLE, Norleucine (C6 H13 N O2, 131.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
NLE
Formula
C6 H13 N O2
Class
ligand
Structures
2
PDB entries
2

Binding sites

NLE in 2 structures; the first of them:

  • 1MMT · Crystal structure of ternary complex of the catalytic domain of human phenylalanine… · NLE A1427 · binds TYR138, ARG270, TYR277, THR278, PRO279, GLU280, PRO281, HIS285 and 6 more
  • 5M3Z · Crystal structure of Citrobacter freundii methionine gamma-lyase with C115H replacement… · NLE A402 · binds TYR113, HIS115, LYS210, VAL338, SER339, LEU340, ARG374

Residues it binds most

SER 2, TYR 2, ARG 2, GLU 1, HIS 2, PRO 1, GLY 1, LEU 1, LYS 1, PHE 1 (residue and the binding sites it lines).

Found with

  • H4B · 5,6,7,8-tetrahydrobiopterin
  • PLP · Pyridoxal-5'-phosphate
  • PY6 · 2-[O-phosphonopyridoxyl]-amino-hexanoic acid
  • FE2 · Fe (II) ion
  • SO4 · Sulfate ion
  • PGE · Triethylene glycol

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