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UniProt Q544L2

Thymidylate synthase (Q544L2)

Thymidylate synthase (UniProt Q544L2): 2 experimental structures on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q544L2
Protein
Thymidylate synthase
Experimental structures
2
Predicted models
0
Ligands
2
Pockets
14 · 2 records with a druggable one

Structures

2 records of Q544L2 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5FCTMouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate.x-ray diffractionA, BUFP, C2F7 (best 0.77)
5FCTMouse thymidylate synthase in ternary complex with fdump and methylenetetrahydrofolate.x-ray diffractionA, BUFP, C2F7 (best 0.77)

Ligands

  • C2F · 5-methyl-5,6,7,8-tetrahydrofolic acid · in 2 records
  • UFP · 5-fluoro-2'-deoxyuridine-5'-monophosphate · in 2 records

Elsewhere

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