UniProt Q53W17
CRISPR system endoribonuclease Csm6 (Q53W17)
CRISPR system endoribonuclease Csm6 (UniProt Q53W17), EC 3.1.-.-: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q53W17
- Protein
- CRISPR system endoribonuclease Csm6
- EC
- 3.1.-.-
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 54 · 5 records with a druggable one
Structures
6 records of Q53W17 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FSH | Crystal structure of Thermus thermophilus Csm6 | x-ray diffraction | A, B | NI | 12 (best 0.71) |
| 5FSH | Crystal structure of thermus thermophilus CSM6 | x-ray diffraction | A, B | NI | 12 (best 0.71) |
| 8JBB | Crystal Structure of the Csm6 from Thermus thermophilus HB8 in complex with A2>p | x-ray diffraction | A, B | — | 6 (best 0.70) |
| 8JBC | Crystal Structure of the Csm6 K137A mutant from Thermus thermophilus HB8 in its apo form | x-ray diffraction | A, B | NI | 10 (best 0.69) |
| 8JH1 | Crystal Structure of the Csm6 Y161A mutant from Thermus thermophilus HB8 in complex with… | x-ray diffraction | A, B | — | 9 (best 0.79) |
| Q53W17 | AlphaFold monomer V2.0 prediction for CRISPR system endoribonuclease CSM6 (Q53W17) | predicted | A | — | 5 (best 0.45) |
Ligands
- NI · Nickel (II) ion · in 3 records
Experiment against prediction
- 8JBB chain A against the predicted model Q53W17: TM-score 0.95, RMSD 1.89 Å
- 8JBC chain A against the predicted model Q53W17: TM-score 0.93, RMSD 2.10 Å
- 8JBB chain B against the predicted model Q53W17: TM-score 0.93, RMSD 2.20 Å
- 5FSH chain A against the predicted model Q53W17: TM-score 0.93, RMSD 2.16 Å
- 5FSH chain A against the predicted model Q53W17: TM-score 0.93, RMSD 2.16 Å
- 8JH1 chain B against the predicted model Q53W17: TM-score 0.92, RMSD 2.31 Å
- 8JBC chain B against the predicted model Q53W17: TM-score 0.92, RMSD 2.42 Å
- 5FSH chain B against the predicted model Q53W17: TM-score 0.91, RMSD 2.41 Å
- 5FSH chain B against the predicted model Q53W17: TM-score 0.91, RMSD 2.41 Å
- 8JH1 chain A against the predicted model Q53W17: TM-score 0.88, RMSD 2.96 Å
Elsewhere
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