UniProt Q4TVQ0
Listeriolysin positive regulatory factor A (Q4TVQ0)
Listeriolysin positive regulatory factor A (UniProt Q4TVQ0): 32 experimental structures on GenesisL1, 8 ligands bound, 115 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4TVQ0
- Protein
- Listeriolysin positive regulatory factor A
- Experimental structures
- 32
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 115 · 13 records with a druggable one
Structures
32 records of Q4TVQ0 in the MolNFT archive: 32 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LRR | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione | x-ray diffraction | A, B, C, D, E, F, G, H | GSH, NA, PI | — |
| 5LRR | The transcriptional regulator prfa from listeria monocytogenes in complex with glutathione | x-ray diffraction | A, B, C, D, E, F, G, H | GSH, NA, PI | — |
| 5LRS | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a… | x-ray diffraction | A, B | GSH | 15 (best 0.73) |
| 5LRS | The transcriptional regulator prfa from listeria monocytogenes in complex with glutathione and a… | x-ray diffraction | A, B | GSH | — |
| 5X6D | Crystal structure of PrfA-DNA binary complex | x-ray diffraction | A, B, G, H, M, N | — | — |
| 5X6D | Crystal structure of prfa-DNA binary complex | x-ray diffraction | A, B, G, H, M, N | — | — |
| 5X6E | Crystal structure of PrfA-DNA binary complex | x-ray diffraction | M, N, A, B, E, F | GSH | 20 (best 0.79) |
| 5X6E | Crystal structure of prfa-DNA binary complex | x-ray diffraction | M, N, A, B, E, F | GSH | — |
| 6EUU | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | NA, K29 | 6 (best 0.84) |
| 6EUU | The transcriptional regulator prfa from listeria monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | NA, K29 | — |
| 6EUZ | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | NA, C8Q | 3 (best 0.87) |
| 6EUZ | The transcriptional regulator prfa from listeria monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | NA, C8Q | — |
| 6EXL | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | C2Q, NA | 2 (best 0.83) |
| 6EXL | The transcriptional regulator prfa from listeria monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | C2Q, NA | — |
| 6EXM | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | QQH, NA | 4 (best 0.78) |
| 6EXM | The transcriptional regulator prfa from listeria monocytogenes in complex with a ring-fused… | x-ray diffraction | A, B | QQH, NA | — |
| 6QVZ | The Transcriptional Regulator PrfA-L140H mutant from Listeria Monocytogenes | x-ray diffraction | A, B | NA | 5 (best 0.79) |
| 6QVZ | The transcriptional regulator prfa-L140H mutant from listeria monocytogenes | x-ray diffraction | A, B | NA | — |
| 6QW1 | The Transcriptional Regulator PrfA-L140F mutant from Listeria Monocytogenes | x-ray diffraction | A, B | NA | — |
| 6QW1 | The transcriptional regulator prfa-L140F mutant from listeria monocytogenes | x-ray diffraction | A, B | NA | — |
| 6QW2 | The Transcriptional Regulator PrfA-A218G mutant from Listeria Monocytogenes | x-ray diffraction | A, B | NA | 4 (best 0.83) |
| 6QW2 | The transcriptional regulator prfa-A218G mutant from listeria monocytogenes | x-ray diffraction | A, B | NA | — |
| 6QWF | The Transcriptional Regulator PrfA-A94V mutant from Listeria Monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | 13 (best 0.76) |
| 6QWF | The transcriptional regulator prfa-A94V mutant from listeria monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | — |
| 6QWH | The Transcriptional Regulator PrfA-L140H mutant from Listeria Monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | 13 (best 0.75) |
| 6QWH | The transcriptional regulator prfa-L140H mutant from listeria monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | — |
| 6QWK | The Transcriptional Regulator PrfA-L140F mutant from Listeria Monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | 12 (best 0.76) |
| 6QWK | The transcriptional regulator prfa-L140F mutant from listeria monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | — |
| 6QWM | The Transcriptional Regulator PrfA-A218G mutant from Listeria Monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | 13 (best 0.76) |
| 6QWM | The transcriptional regulator prfa-A218G mutant from listeria monocytogenes in complex with a 30-bp… | x-ray diffraction | A, B | — | — |
| 6T5I | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with inhibitor of WNT… | x-ray diffraction | A, B | 9XK, NA | 5 (best 0.77) |
| 6T5I | The transcriptional regulator prfa from listeria monocytogenes in complex with inhibitor of wnt… | x-ray diffraction | A, B | 9XK, NA | — |
Ligands
- NA · Sodium ion · in 18 records
- GSH · Glutathione · in 6 records
- 9XK · ~{N}-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxidanylidene-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]ethanamide · in 2 records
- C2Q · [(3~{R})-3-carboxy-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium · in 2 records
- C8Q · (3~{R})-8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid · in 2 records
- K29 · (3~{R})-8-cyclopropyl-5-oxidanylidene-7-(quinolin-3-ylmethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid · in 2 records
- PI · Hydrogenphosphate ion · in 2 records
- QQH · [(3~{R})-3-carboxy-7-[(2,3-dimethylphenyl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium · in 2 records
Elsewhere
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