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UniProt Q4QBL1

Farnesyl pyrophosphate synthase (Q4QBL1)

Farnesyl pyrophosphate synthase (UniProt Q4QBL1), EC 2.5.1.1, 2.5.1.10: 12 experimental structures on GenesisL1, 3 ligands bound, 24 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q4QBL1
Protein
Farnesyl pyrophosphate synthase
EC
2.5.1.1, 2.5.1.10
Experimental structures
12
Predicted models
0
Ligands
3
Pockets
24 · 3 records with a druggable one

Structures

12 records of Q4QBL1 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4JZBCrystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with…x-ray diffractionA, B——
4JZBCrystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with…x-ray diffractionA, B——
4JZXCrystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with…x-ray diffractionA, B——
4JZXCrystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with…x-ray diffractionA, B——
4K10Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with…x-ray diffractionA, B, D, C——
4K10Crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with…x-ray diffractionA, B, D, C——
6VJCLmFPPS mutant T164Y in complex with 476A, IPP & Cax-ray diffractionA, BCA, IPR, 4768 (best 0.84)
6VJCLmfpps mutant T164Y in complex with 476A, ipp & cax-ray diffractionA, BCA, IPR, 476—
6W7ILmFPPS mutant T164W in complex with 476A, IPP & Cax-ray diffractionA, BCA, IPR, 4768 (best 0.83)
6W7ILmfpps mutant T164W in complex with 476A, ipp & cax-ray diffractionA, BCA, IPR, 476—
6WW1Crystal structure of the LmFPPS mutant E97Yx-ray diffractionA, BCA, IPR, 4768 (best 0.83)
6WW1Crystal structure of the lmfpps mutant E97Yx-ray diffractionA, BCA, IPR, 476—

Ligands

  • 476 · 3-butyl-1-(2,2-diphosphonoethyl)pyridinium · in 6 records
  • CA · Calcium ion · in 6 records
  • IPR · Isopentyl pyrophosphate · in 6 records

Elsewhere

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