UniProt Q4J989
Homocitrate synthase (Q4J989)
Homocitrate synthase (UniProt Q4J989), EC 2.3.3.14: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q4J989
- Protein
- Homocitrate synthase
- EC
- 2.3.3.14
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 4 · 1 record with a druggable one
Structures
3 records of Q4J989 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KTQ | Crystal structure of catalytic domain of homocitrate synthase from Sulfolobus acidocaldarius… | x-ray diffraction | A, B | ZN, AKG, COA, SO4 | 4 (best 0.71) |
| 6KTQ | Crystal structure of catalytic domain of homocitrate synthase from sulfolobus acidocaldarius… | x-ray diffraction | A, B | ZN, AKG, COA, SO4 | — |
| Q4J989 | AlphaFold monomer V2.0 prediction for homocitrate synthase (Q4J989) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6KTQ chain B against the predicted model Q4J989: TM-score 0.96, RMSD 0.94 Å
- 6KTQ chain B against the predicted model Q4J989: TM-score 0.96, RMSD 0.94 Å
- 6KTQ chain A against the predicted model Q4J989: TM-score 0.95, RMSD 1.12 Å
- 6KTQ chain A against the predicted model Q4J989: TM-score 0.95, RMSD 1.12 Å
Elsewhere
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