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UniProt Q4E4L7

Isocitrate dehydrogenase [NADP] (Q4E4L7)

Isocitrate dehydrogenase [NADP] (UniProt Q4E4L7), EC 1.1.1.42: 2 experimental structures on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q4E4L7
Protein
Isocitrate dehydrogenase [NADP]
EC
1.1.1.42
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
20 · 1 record with a druggable one

Structures

2 records of Q4E4L7 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6AJCCrystal structure of Trypanosoma cruzi cytosolic isocitrate dehydrogenase in complex with NADP+…x-ray diffractionA, B, C, D, E, F, G, HNAP, CA, ICT20 (best 0.84)
6AJCCrystal structure of trypanosoma cruzi cytosolic isocitrate dehydrogenase in complex with NADP+…x-ray diffractionA, B, C, D, E, F, G, HNAP, CA, ICT—

Ligands

  • CA · Calcium ion · in 2 records
  • ICT · Isocitric acid · in 2 records
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 2 records

Elsewhere

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