UniProt Q4E4E1
Glucokinase 1, putative (Q4E4E1)
Glucokinase 1, putative (UniProt Q4E4E1), EC 2.7.1.2: 14 experimental structures on GenesisL1, 7 ligands bound, 53 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4E4E1
- Protein
- Glucokinase 1, putative
- EC
- 2.7.1.2
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 53 · 7 records with a druggable one
Structures
14 records of Q4E4E1 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2Q2R | Trypanosoma cruzi glucokinase in complex with beta-D-glucose and ADP | x-ray diffraction | A, B | BGC, ADP | 8 (best 0.73) |
| 2Q2R | Trypanosoma cruzi glucokinase in complex with beta-D-glucose and ADP | x-ray diffraction | A, B | BGC, ADP | 8 (best 0.73) |
| 5BRD | Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor benz-glcn | x-ray diffraction | A, B | — | — |
| 5BRE | Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor cbz-glcn | x-ray diffraction | A, B | — | — |
| 5BRF | Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor HPOP-GlcN | x-ray diffraction | A, B | 4V5 | 7 (best 0.72) |
| 5BRF | Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor hpop-glcn | x-ray diffraction | A, B | — | — |
| 5BRH | Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor DBT-GlcN | x-ray diffraction | A, B | 4V3 | 12 (best 0.73) |
| 5BRH | Crystal structure of trypanosoma cruzi glucokinase in complex with inhibitor dbt-glcn | x-ray diffraction | A, B | — | — |
| 7S2H | Crystal structure of Trypanosoma cruzi glucokinase in the apo form (open conformation) | x-ray diffraction | A, B | NA, SO4 | 4 (best 0.76) |
| 7S2H | Crystal structure of trypanosoma cruzi glucokinase in the apo form (open conformation) | x-ray diffraction | A, B | NA, SO4 | — |
| 7S2N | Crystal structure of the F337L mutation of Trypanosoma cruzi glucokinase in the apo form (open… | x-ray diffraction | A, B | — | 4 (best 0.75) |
| 7S2N | Crystal structure of the F337L mutation of trypanosoma cruzi glucokinase in the apo form (open… | x-ray diffraction | A, B | — | — |
| 7S2P | Crystal structure of the F337L mutation of Trypanosoma cruzi glucokinase in complex with inhibitor… | x-ray diffraction | A, B | 4UZ, SO4 | 10 (best 0.74) |
| 7S2P | Crystal structure of the F337L mutation of trypanosoma cruzi glucokinase in complex with inhibitor… | x-ray diffraction | A, B | 4UZ, SO4 | — |
Ligands
- SO4 · Sulfate ion · in 4 records
- 4UZ · 2-{[(benzyloxy)carbonyl]amino}-2-deoxy-beta-D-glucopyranose · in 2 records
- ADP · Adenosine-5'-diphosphate · in 2 records
- BGC · beta-D-glucopyranose · in 2 records
- NA · Sodium ion · in 2 records
- 4V3 · 2-deoxy-2-({[(1,1-dioxido-1-benzothiophen-2-yl)methoxy]carbonyl}amino)-beta-D-glucopyranose · in 1 record
- 4V5 · 2-deoxy-2-{[3-(4-hydroxyphenyl)propanoyl]amino}-alpha-D-glucopyranose · in 1 record
Elsewhere
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