UniProt Q48MT7
Renalase (Q48MT7)
Renalase (UniProt Q48MT7), EC 1.6.3.5: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q48MT7
- Protein
- Renalase
- EC
- 1.6.3.5
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 2 records with a druggable one
Structures
5 records of Q48MT7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ZCC | Renalase in complex with NADH | x-ray diffraction | A, B, C, D | FAD, NAI | 11 (best 0.87) |
| 4ZCC | Renalase in complex with NADH | x-ray diffraction | A, B, C, D | — | — |
| 4ZCD | Renalase in complex with NAD+ | x-ray diffraction | A, B | — | — |
| 4ZCD | Renalase in complex with NAD+ | x-ray diffraction | A, B | — | — |
| Q48MT7 | AlphaFold monomer V2.0 prediction for renalase (Q48MT7) | predicted | A | — | 1 (best 0.77) |
Ligands
Experiment against prediction
- 4ZCD chain A against the predicted model Q48MT7: TM-score 0.99, RMSD 0.55 Å
- 4ZCD chain A against the predicted model Q48MT7: TM-score 0.99, RMSD 0.55 Å
- 4ZCD chain B against the predicted model Q48MT7: TM-score 0.99, RMSD 0.35 Å
- 4ZCD chain B against the predicted model Q48MT7: TM-score 0.99, RMSD 0.35 Å
- 4ZCC chain B against the predicted model Q48MT7: TM-score 0.99, RMSD 0.74 Å
- 4ZCC chain B against the predicted model Q48MT7: TM-score 0.99, RMSD 0.74 Å
- 4ZCC chain A against the predicted model Q48MT7: TM-score 0.99, RMSD 0.74 Å
- 4ZCC chain A against the predicted model Q48MT7: TM-score 0.99, RMSD 0.74 Å
- 4ZCC chain D against the predicted model Q48MT7: TM-score 0.99, RMSD 0.48 Å
- 4ZCC chain D against the predicted model Q48MT7: TM-score 0.99, RMSD 0.48 Å
Elsewhere
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