UniProt Q47112
Colicin E7 (Q47112)
Colicin E7 (UniProt Q47112), EC 3.1.-.-: 34 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q47112
- Protein
- Colicin E7
- EC
- 3.1.-.-
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 43 · 3 records with a druggable one
Structures
35 records of Q47112 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M08 | Crystal structure of the unbound nuclease domain of ColE7 | x-ray diffraction | A, B | ZN, PO4 | 4 (best 0.39) |
| 1M08 | Crystal structure of the unbound nuclease domain of COLE7 | x-ray diffraction | A, B | — | — |
| 1MZ8 | Crystal structures of the nuclease domain of COLE7/IM7 in complex with a phosphate ion and a zinc… | x-ray diffraction | B, D | ZN, PO4 | 8 (best 0.69) |
| 1MZ8 | Crystal structures of the nuclease domain of COLE7/IM7 in complex with a phosphate ion and a zinc… | x-ray diffraction | B, D | — | — |
| 1PT3 | Crystal structures of nuclease-ColE7 complexed with octamer DNA | x-ray diffraction | A, B | — | 8 (best 0.63) |
| 1PT3 | Crystal structures of nuclease-COLE7 complexed with octamer DNA | x-ray diffraction | A, B | — | — |
| 1UJZ | Crystal structure of the E7_C/Im7_C complex; a computationally designed interface between the… | x-ray diffraction | B | — | 3 (best 0.48) |
| 1UJZ | Crystal structure of the E7_C/IM7_C complex; a computationally designed interface between the… | x-ray diffraction | B | — | — |
| 1ZNS | Crystal structure of N-ColE7/12-bp DNA/Zn complex | x-ray diffraction | A | ZN | 4 (best 0.46) |
| 1ZNS | Crystal structure of N-COLE7/12-bp DNA/ZN complex | x-ray diffraction | A | — | — |
| 1ZNV | How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor | x-ray diffraction | B, D | NI, PO4 | 8 (best 0.70) |
| 1ZNV | How a his-metal finger endonuclease COLE7 binds and cleaves DNA with a transition metal ion cofactor | x-ray diffraction | B, D | — | — |
| 2AXC | Crystal structure of ColE7 translocation domain | x-ray diffraction | A | SO4 | 2 (best 0.39) |
| 2AXC | Crystal structure of COLE7 translocation domain | x-ray diffraction | A | — | — |
| 2ERH | Crystal Structure of the E7_G/Im7_G complex; a designed interface between the colicin E7 DNAse and… | x-ray diffraction | B | — | 1 (best 0.43) |
| 2ERH | Crystal structure of the E7_G/IM7_G complex; a designed interface between the colicin E7 DNase and… | x-ray diffraction | B | — | — |
| 2IVH | Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA | x-ray diffraction | A | — | — |
| 2IVH | Crystal structure of the nuclease domain of COLE7 (H545Q mutant) in complex with an 18-bp duplex DNA | x-ray diffraction | A | — | — |
| 2JAZ | Crystal structure of the mutant N560D of the nuclease domain of COLE7 in complex with IM7 | x-ray diffraction | B, D | — | — |
| 2JAZ | Crystal structure of the mutant N560D of the nuclease domain of COLE7 in complex with IM7 | x-ray diffraction | B, D | — | — |
| 2JB0 | Crystal structure of the mutant H573A of the nuclease domain of COLE7 in complex with IM7 | x-ray diffraction | B | — | — |
| 2JB0 | Crystal structure of the mutant H573A of the nuclease domain of COLE7 in complex with IM7 | x-ray diffraction | B | — | — |
| 2JBG | crystal structure of the mutant N560A of the nuclease domain of ColE7 in complex with Im7 | x-ray diffraction | B, D | — | — |
| 2JBG | Crystal structure of the mutant N560A of the nuclease domain of COLE7 in complex with IM7 | x-ray diffraction | B, D | — | — |
| 3FBD | Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-BP duplex DNA | x-ray diffraction | A, D | — | — |
| 3FBD | Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-bp duplex DNA | x-ray diffraction | A, D | — | — |
| 3GJN | Following evolutionary paths to high affinity and selectivity protein-protein interactions using… | x-ray diffraction | B, C | — | — |
| 3GJN | Following evolutionary paths to high affinity and selectivity protein- protein interactions using… | x-ray diffraction | B, C | — | — |
| 3GKL | Following evolutionary paths to high affinity and selectivity protein-protein interactions using… | x-ray diffraction | A, B | — | — |
| 3GKL | Following evolutionary paths to high affinity and selectivity protein- protein interactions using… | x-ray diffraction | A, B | — | — |
| 3ZFK | N-terminal truncated Nuclease Domain of Colicin E7 | x-ray diffraction | A, B | — | — |
| 3ZFK | N-terminal truncated nuclease domain of colicin E7 | x-ray diffraction | A, B | — | — |
| 7CEI | The endonuclease domain of colicin E7 in complex with its inhibitor IM7 protein | x-ray diffraction | B | ZN | 5 (best 0.42) |
| 7CEI | The endonuclease domain of colicin E7 in complex with its inhibitor IM7 protein | x-ray diffraction | B | ZN | — |
| Q47112 | AlphaFold monomer V2.0 prediction for colicin-E7 (Q47112) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2JAZ chain B against the predicted model Q47112: TM-score 0.98, RMSD 0.56 Å
- 2JAZ chain B against the predicted model Q47112: TM-score 0.98, RMSD 0.56 Å
- 3FBD chain D against the predicted model Q47112: TM-score 0.98, RMSD 0.62 Å
- 3FBD chain D against the predicted model Q47112: TM-score 0.98, RMSD 0.62 Å
- 3FBD chain A against the predicted model Q47112: TM-score 0.98, RMSD 0.60 Å
- 3FBD chain A against the predicted model Q47112: TM-score 0.98, RMSD 0.60 Å
- 2JAZ chain D against the predicted model Q47112: TM-score 0.98, RMSD 0.58 Å
- 2JAZ chain D against the predicted model Q47112: TM-score 0.98, RMSD 0.58 Å
- 2JB0 chain B against the predicted model Q47112: TM-score 0.98, RMSD 0.58 Å
- 2JB0 chain B against the predicted model Q47112: TM-score 0.98, RMSD 0.58 Å
Elsewhere
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