UniProt Q45697
Uric acid degradation bifunctional protein (Q45697)
Uric acid degradation bifunctional protein (UniProt Q45697), EC 1.7.3.3, 4.1.1.97: 28 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 184 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q45697
- Protein
- Uric acid degradation bifunctional protein
- EC
- 1.7.3.3, 4.1.1.97
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 184 · 29 records with a druggable one
Structures
29 records of Q45697 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J2G | Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine | x-ray diffraction | A, B, C, D | SO4, AZA | 13 (best 0.77) |
| 1J2G | Crystal structure of urate oxidase from bacillus sp. tb-90 co- crystallized with 8-azaxanthine | x-ray diffraction | A, B, C, D | SO4, AZA | 13 (best 0.77) |
| 3WLV | Thermostable urate oxidase from Bacillus sp. TB-90 | x-ray diffraction | A, B, C, D | AZA, SO4, CL, K | 9 (best 0.76) |
| 3WLV | Thermostable urate oxidase from bacillus sp. tb-90 | x-ray diffraction | A, B, C, D | AZA, SO4, CL, K | 9 (best 0.76) |
| 4XFP | Crystal structure of highly active mutant of bacillus sp. tb-90 urate oxidase | x-ray diffraction | A, B, C, D | AZA, CL, SO4 | 9 (best 0.76) |
| 5AYJ | Hyperthermostable mutant of Bacillus sp. TB-90 Urate Oxidase - R298C | x-ray diffraction | A, B, C, D | MUA, SO4 | 6 (best 0.75) |
| 5AYJ | Hyperthermostable mutant of bacillus sp. tb-90 urate oxidase - R298C | x-ray diffraction | A, B, C, D | MUA, SO4 | 6 (best 0.75) |
| 5Y2P | Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 89% RH | x-ray diffraction | A, B | AZA, OXY, SO4, K | 5 (best 0.66) |
| 5Y2P | Crystal structure of bacillus sp. tb-90 urate oxidase improved by humidity control at 89% rh | x-ray diffraction | A, B | AZA, OXY, SO4, K | 5 (best 0.66) |
| 5Y52 | Crystal Structure of Highly Active BTUO Mutant P287G Improved by Humidity Control at 83% RH | x-ray diffraction | A, B, C, D | AZA, OXY, SO4 | 6 (best 0.77) |
| 5Y52 | Crystal structure of highly active btuo mutant P287G improved by humidity control at 83% rh | x-ray diffraction | A, B, C, D | AZA, OXY, SO4 | 6 (best 0.77) |
| 5YJ2 | Crystal structure of Bacillus sp. TB-90 urate oxidase without dehydration | x-ray diffraction | A, B, C, D | AZA, OXY, SO4 | 7 (best 0.77) |
| 5YJ2 | Crystal structure of bacillus sp. tb-90 urate oxidase without dehydration | x-ray diffraction | A, B, C, D | AZA, OXY, SO4 | 7 (best 0.77) |
| 5YJA | Crystal structure of highly active BTUO mutant P287G without dehydration | x-ray diffraction | A, B, C, D | AZA, OXY, SO4, K | 7 (best 0.78) |
| 5YJA | Crystal structure of highly active btuo mutant P287G without dehydration | x-ray diffraction | A, B, C, D | AZA, OXY, SO4, K | 7 (best 0.78) |
| 5Z27 | Crystal structure of highly active BTUO mutant P287G without dehydration | x-ray diffraction | A, B | AZA, SO4, OXY, K | 4 (best 0.70) |
| 5Z27 | Crystal structure of highly active btuo mutant P287G without dehydration | x-ray diffraction | A, B | AZA, SO4, OXY, K | 4 (best 0.70) |
| 5Z2B | Crystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86% RH | x-ray diffraction | A, B | AZA, SO4, OXY, CL | 4 (best 0.66) |
| 5Z2B | Crystal structure of highly active btuo mutant P287G improved by humidity control at 86% rh | x-ray diffraction | A, B | AZA, SO4, OXY, CL | 4 (best 0.66) |
| 7CMN | Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 88% RH. | x-ray diffraction | A, B | AZA, OXY, SO4 | 5 (best 0.66) |
| 7CMN | Crystal structure of bacillus sp. tb-90 urate oxidase improved by humidity control at 88% rh. | x-ray diffraction | A, B | AZA, OXY, SO4 | 5 (best 0.66) |
| 7CMQ | Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 88% RH. | x-ray diffraction | A, B | AZA, OXY, SO4 | 4 (best 0.66) |
| 7CMQ | Crystal structure of bacillus sp. tb-90 urate oxidase improved by humidity control at 88% rh. | x-ray diffraction | A, B | AZA, OXY, SO4 | 4 (best 0.66) |
| 7CUC | Crystal structure of urate oxidase from bacillus sp. tb-90 in the absence from chloride anion at… | x-ray diffraction | A, B | AZA, OXY, NA, SO4 | 6 (best 0.67) |
| 7CUF | Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride Anion at… | x-ray diffraction | A, B | AZA, OXY, NA, SO4 | 6 (best 0.66) |
| 7CUF | Crystal structure of urate oxidase from bacillus sp. tb-90 in the absence from chloride anion at… | x-ray diffraction | A, B | AZA, OXY, NA, SO4 | 6 (best 0.66) |
| 7CUG | Crystal Structure of Urate Oxidase from Bacillus sp. TB-90 in the absence from Chloride Anion at… | x-ray diffraction | A, B | AZA, OXY, SO4, NA | 6 (best 0.66) |
| 7CUG | Crystal structure of urate oxidase from bacillus sp. tb-90 in the absence from chloride anion at… | x-ray diffraction | A, B | AZA, OXY, SO4, NA | 6 (best 0.66) |
| Q45697 | AlphaFold monomer V2.0 prediction for uric acid degradation bifunctional protein (Q45697) | predicted | A | — | 5 (best 0.62) |
Ligands
Experiment against prediction
- 7CUC chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.25 Å
- 7CUF chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.26 Å
- 7CUF chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.26 Å
- 7CMQ chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.27 Å
- 7CMQ chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.27 Å
- 5Y2P chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.27 Å
- 5Y2P chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.27 Å
- 7CMN chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.27 Å
- 7CMN chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.27 Å
- 7CUG chain A against the predicted model Q45697: TM-score 1.00, RMSD 0.28 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.